| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
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| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| Broca's pouch | A pear-shaped encapsulated collection of connective tissue and fat in each labium majus. Synonym: Broca's pouch. (05 Mar 2000) |
| paracystic pouch | A peritoneal depression formed by the reflection of the peritoneum from the lateral pelvic wall onto the roof of the bladder; in the female, it is the lateral portion of the uterovesical pouch, separated from the pararectal pouch by the broad ligament. Synonym: fossa paravesicalis, paracystic pouch, paravesical pouch. (05 Mar 2000) |
| Rathke's pouch | A tubular outgrowth of ectoderm from the stomodeum of the embryo; it grows dorsad toward the infundibular process of the diencephalon, around which it forms a cup-like mass, giving rise to the pars distalis and pars juxtaneuralis of the hypophysis. Synonym: craniopharyngeal canal, hypophyseal pouch, Rathke's diverticulum, Rathke's pocket, Rathke's pouch. (05 Mar 2000) |
| Rathke's pouch tumour | <oncology, tumour> A form of primary brain tumour which develops in the pituitary gland. These tumours often secrete increased quantities of pituitary hormones (for example growth hormone) which can result in conditions such as gigantism and acromegaly. They are often benign and rare and comprise less than 5% of childhood brain tumours. Other symptoms include vision changes, headache and weight gain. Treatment often includes a combination of surgery and radiation therapy. (27 Sep 1997) |
| pararectal pouch | A peritoneal depression on either side of the rectum formed by peritoneal (sacrogenital) folds passing from the posterolateral pelvic wall to the central pelvic viscera. The fossa is a lateral extension of the male rectovesical pouch or the female rectouterine pouch. Synonym: pararectal pouch. (05 Mar 2000) |
| paravesical pouch | A peritoneal depression formed by the reflection of the peritoneum from the lateral pelvic wall onto the roof of the bladder; in the female, it is the lateral portion of the uterovesical pouch, separated from the pararectal pouch by the broad ligament. Synonym: fossa paravesicalis, paracystic pouch, paravesical pouch. (05 Mar 2000) |
| rectouterine pouch | <anatomy> A pocket formed by the deflection of the peritoneum from the rectum to the uterus. Synonym: excavatio rectouterina, cavum douglasi, cul-de-sac, Douglas' cul-de-sac, Douglas' pouch, pouch of Douglas, rectovaginouterine pouch. (05 Mar 2000) |
| rectovaginouterine pouch | <anatomy> A pocket formed by the deflection of the peritoneum from the rectum to the uterus. Synonym: excavatio rectouterina, cavum douglasi, cul-de-sac, Douglas' cul-de-sac, Douglas' pouch, pouch of Douglas, rectovaginouterine pouch. (05 Mar 2000) |
| rectovesical pouch | A pocket formed by the deflection of the peritoneum from the rectum to the bladder in the male. Synonym: excavatio rectovesicalis, Proust's space. (05 Mar 2000) |