| TTNB | Transient Tachypnea of New Born |
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| ANDA | Abbreviated New Drug Application |
| IND | indomethacin; industrial medicine; investigational new drug |
| NAD | neutrophil actin dysfunction; new antigenic determinant; nicotinamide adenine dinucleotide; nicotini... |
| NADA | New Animal Drug Application |
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
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| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| Abegg's rule | The tendency of the sum of the maximum positive and maximum negative valence of a particular element to equal 8; e.g., C may have a valence of +4 and -4, O of +6 and -2. Sometimes loosely stated as all atoms have the same number of valences, a consequence of the tendency of valence electron shells to be filled to 8. (05 Mar 2000) |
| American Law Institute rule | A test of criminal responsibility (1962): "a person is not responsible for criminal conduct if at the time of such conduct as a result of mental disease or defect he lacks substantial capacity either to appreciate the wrongfulness of his conduct or to conform his conduct to the requirements of law." (05 Mar 2000) |
| astigmatism against the rule | Astigmatism when the greater curvature or refractive power is in the horizontal meridian. (05 Mar 2000) |
| astigmatism with the rule | Astigmatism when the greater curvature or refractive power is in the vertical meridian. (05 Mar 2000) |
| pair rule gene | <molecular biology> A segmentation gene, expressed sequentially between gap genes and segment polarity genes. In development of Drosophila, a set of about 8 genes that are expressed only in alternate segments (odd or even) of the developing embryo. Loss of function mutants thus lack alternate segments. Examples: even skipped (eve), fushi tarazu (ftz), hairy. (18 Nov 1997) |
| Gibb's phase rule | An expression of the relationships existing between systems in equilibrium: P + V = C + 2, where P is the number of phases, V the variance or degrees of freedom, and C the number of components; it also follows that the variance is, V = C + 2 -P. For H2O at its triple point, V = 1 + 2 -3 = 0, i.e., both temperature and pressure are fixed. Synonym: Gibb's phase rule. (05 Mar 2000) |
| Gloger's rule | The rule or observation that the skin of a warm-blooded animal species tends to become darker in colour towards warmer climates at lower altitudes or lower latitudes, and to become lighter in colour towards colder climates at higher altitudes or higher latitudes. (09 Oct 1997) |
| Goriaew's rule | Rarely used term for a rule of a blood counting field by which it is marked off in a series of squares, some of which are again subdivided into sixteen smaller ones. (05 Mar 2000) |
| Chargaff's rule | In DNA the number of adenine units equals the number of thymine units; likewise, the number of guanine units equals the number of cytosine units. (05 Mar 2000) |
| gt-ag rule | This is the observation that all introns in DNA begin with the nucleotides of GT(guanine, thymine) and end with the nucleotides AG (adenine, guanine). When the DNA is transcribed into RNA, the introns are removed from the RNA by a mechanism which recognises these beginning and ending nucleotides - in the RNA they would be CU (cytosine, uracil) and AC (adenine, cytosine). (09 Oct 1997) |
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