| new mutation | Redundant term for a heritable trait present in the offspring but in neither parent, i.e., not a pre-existing mutant form inherited. (05 Mar 2000) |
|---|---|
| new south wales | A state in southeastern Australia. Its capital is sydney. It was discovered by captain cook in 1770 and first settled at botany bay by marines and convicts in 1788. It was named by captain cook who thought its coastline resembled that of south wales. (12 Dec 1998) |
| New World leishmaniasis | A grave disease caused by Leishmania braziliensis braziliensis, endemic in southern Mexico and Central and South America, except for the equatorial region of Chile; the organism does not invade the viscera, and the disease is limited to the skin and mucous membranes, the lesions resembling the sores of cutaneous leishmaniasis caused by L. Mexicana or L. Tropica; the chancrous sores heal after a time, but some months or years later, fungating and eroding forms of ulceration may appear on the tongue and buccal or nasal mucosa; many variants of the disease exist, marked by differences in distribution, vector, epidemiology, and pathology, which suggest that it may in fact be caused by a number of closely related aetiological agents. See: espundia. Synonym: American leishmaniasis, leishmaniasis americana, nasopharyngeal leishmaniasis, New World leishmaniasis. (05 Mar 2000) |
| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| Abbe theory of image formation | <optics, physics> Abbe's theory is based on the fact that a non-self-luminous particle, which is illuminated by an extraneous source, gives rise to diffracted light rays, in addition to the dioptric pencil. He stated that to form a good microscopical image as many of the diffracted rays as possible should be intercepted by the objective. With closely ruled lines, his theory is easily demonstrated by observing the back lens of the objective, for here the diffracted rays can be observed directly if the aperture diaphragm is closed. It can be shown that, when the illumination is arranged to exclude the diffracted images, resolution is lost. (11 Mar 1998) |
| accidental image | Continuation of visual impression after cessation of stimuli causing the original image. (12 Dec 1998) |
| body image | A term for the concept which each individual has of his own body as an object in and bound by space, independently and apart from all other objects. (12 Dec 1998) |
| radiographic image enhancement | Improvement in the quality of an X-ray image by use of an intensifying screen, tube, or filter and by optimum exposure techniques. Digital processing methods are often employed. (12 Dec 1998) |
| radiographic image interpretation, computer-assisted | Computer systems or networks designed to provide radiographic interpretive information. (12 Dec 1998) |
| real image | An image formed by the convergence of the actual rays of light from an object. Synonym: inverted image. (05 Mar 2000) |