| AGMkK | African green monkey kidney [cell] |
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| AHS | Academy of Health Sciences; African horse sickness; alveolar hypoventilation syndrome; American Hear... |
| ASF | African swine fever; aniline-sulfur-formaldehyde [resin] |
| ASP | abnormal spinal posture; acute symmetric polyarthritis; African swine pox; aged substrate plasma; al... |
| IBED | Inter-African Bureau for Epizootic Diseases |
| new yellow enzyme | The d-amino-acid oxidase found in yeast, a flavoenzyme, which contains FAD as coenzyme instead of FMN as does NADPH dehydrogenase; so-called to distinguish it from Warburg's old yellow enzyme. Compare: amino acid oxidases. (05 Mar 2000) |
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| New York Heart Association classification | A functional classification to assess cardiovascular disability. Class I: patients with cardiac disease without limitation of physical activity. Ordinary activity does not cause symptoms. Class II: patients with cardiac disease with slight limitation of activity; comfortable at rest. Ordinary physical activity results in fatigue, palpitation, dyspnea or angina. Class III: patients with cardiac disease producing marked limitation of activity: comfortable at rest. Less than ordinary physical activity causes symptoms. Class IV: patients with cardiac disease resulting in inability to carry on any physical activity without discomfort. Symptoms may be present even at rest. (05 Mar 2000) |
| new zealand | A group of islands in the South Pacific Ocean. New Zealand flax. <botany> A myrtaceous shrub (Leptospermum scoparium) of new Zealand and Australia, the leaves of which are used as a substitute for tea. Source: Websters Dictionary (01 Mar 1998) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| investigational new drug | Status given an experimental drug after the FDA approves an application for testing it in people. (09 Oct 1997) |
| investigational new drug application | An application that must be submitted to a regulatory agency (the FDA in the united states) before a drug can be studied in humans. This application includes results of previous experiments; how, where, and by whom the new studies will be conducted; the chemical structure of the compound; how it is thought to work in the body; any toxic effects found in animal studies; and how the compound is manufactured. (12 Dec 1998) |
| acute African sleeping sickness | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| african | Of or pertaining to Africa. African hemp, a fibre prerared from the leaves of the Sanseviera Guineensis, a plant found in Africa and India. African marigold, a tropical American plant (Tagetes erecta). African oak or African teak, a timber furnished by Oldfieldia Africana, used in ship building. Origin: L. Africus, Africanus, fr. Afer African. Source: Websters Dictionary (01 Mar 1998) |
| African endomyocardial fibrosis | Fibrosis of the inner layers of the myocardium, often including the endocardium, causing diastolic restriction of the heart; indigenous to East Africa. (05 Mar 2000) |
| African furuncular myiasis | Infection of man and animals with larvae of flies of the genus Cordylobia. Synonym: African furuncular myiasis, tumbu dermal myiasis. (05 Mar 2000) |
| african green monkey kidney cell | <cell culture> Cells taken from the kidneys of the African green monkey Cercopithecus aethiops sabaeus and used to grow certain viruses like poliovirus. (05 Feb 1998) |
| African haemorrhagic fever | Haemorrhagic fever associated with the morphologically similar but antigenically distinct Marburg and Ebola viruses. See: viral haemorrhagic fever. (05 Mar 2000) |
| african horse sickness | An insect-borne reovirus infection of horses, mules and donkeys in africa and the middle east; characterised by pulmonary oedema, cardiac involvement, and oedema of the head and neck. (12 Dec 1998) |
| african horse sickness virus | A species of orbivirus that causes disease in horses, mules, and donkeys. (12 Dec 1998) |
| african sleeping sickness | <infectious disease> A disease affecting humans and other mammals in central Africa that is caused by the parasitic protozoans Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and is transmitted by the tsetse fly. Symptoms include fever, chills, headache, vomiting, pain in the extremities, lymph gland enlargement, anaemia, depression, fatigue, coma, and eventually death if left untreated. The trypanosome is able to evade the host's immune system by frequently changing the proteins on its outer surface, by which the immune system identifies intruders. (05 Feb 1998) |