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sulfur mustard <chemical> 1,1'-thiobis(2-chloroethane). Severe irritant and vesicant of skin, eyes, and lungs. It may cause blindness and lethal lung oedema and was formerly used as a war gas. The substance has been proposed as a cytostatic and for treatment of psoriasis. It has been listed as a known carcinogen in the fourth annual report on carcinogens (ntp-85-002, 1985) (merck, 11th ed).
Pharmacological action: carcinogens, chemical warfare agents, dermatologic agents.
Chemical name: Ethane, 1,1'-thiobis(2-chloro-
(12 Dec 1998)
quinacrine mustard <chemical> 2-methoxy-6-chloro-9-[4-bis(beta-chloroethyl)amino-1-methylbutylamino]acridine. Nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. Fluoresces by reaction with nucleic acids in chromosomes.
Pharmacological action: fluorescent dyes.
Chemical name: 1,4-Pentanediamine, N1,N1-bis(2-chloroethyl)-N4-(6-chloro-2-methoxy-9-acridinyl)-, dihydrochloride
(12 Dec 1998)
expressed mustard oil The fixed oil expressed from the seeds of Brassica alba and B. Nigra; it contains the glycerides of oleic, arachidic, and other fatty acids; used as salad oil and in the manufacture of oleomargarine.
(05 Mar 2000)
uracil mustard <chemical> Nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.
Pharmacological action: antineoplastic agent, alkylating.
Chemical name: 2,4(1H,3H)-Pyrimidinedione, 5-(bis(2-chloroethyl)amino)-
(12 Dec 1998)
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