| 영문 | MVP(=mitral valve prolapse) | 한글 | 승모판 탈출증 |
|---|---|---|---|
| 설명 | 승모판이 좌심실운동시 제대로 닫혀주지 못하고 빠져나오는 상태로서 주로 젊은 여성에게서 발견된다. 다른 말로 청진상의 소견을 따서 “clickmurmur syndrome”이라고도 하고 혹은 처음 발견한 의사의 이름을 따서 “Barlow's syndrome”이라고도 한다. 개 정상적인 삶을 누리게 되나, 일부에서 심내막염(심장내막의 염증: endocarditis)의 위험이 증가하므로 치과적 시술시 예방적 항생제가 필요하기도 하다. |
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| 영문 | mitral valve | 한글 | 승모판막 |
|---|---|---|---|
| 설명 | 좌심실과 좌심방사이에 존재하는 판막. 2개의 막으로 나누어져 있으며, 밑으로 심근과 연결되어 있다. |
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| 영문 | tricuspid valve | 한글 | 오른방실판막, 삼첨판막 |
|---|---|---|---|
| 설명 | 사람과 포유류 심장의 우심방과 우심실 사이에 있는 판. 우측 방실구(심방과 심실을 연락하는 구멍) 주위에서 시작되는 세 개의 얇은 판막과, 그 자유연에 부착되어 있는 많은 끈으로 되어 있다. 건삭은 결합조직으로 된 가는 끈인데, 그 반대쪽 끝의 일부는 우심실벽에 부착되고, 일부는 심실벽에서 뻗어나온 유두근에 부착되어 있다. 이 판막장치는 심실이 이완되어 있을 때 우심방으로부터 우심실로 흘러들어간 혈액이 심실이 수축할 때에 심방으로 역류하는 것을 막는 것으로서 왼쪽에 있는 이첨판에 해당된다. |
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| 영문 | prosthetic valve | 한글 | 인공판막 |
|---|---|---|---|
| 설명 | 심장 내부의 인공판막. 심장의 판막이 어떤 원인으로 손상되어 판막의 기능이 유지될 수 없을 때 이 판막을 성형해서 다시 사용하거나(판막성형술) 인공판막으로 치환(판막치환술)해 주어야 한다. 인공판막에는 크게 두 가지가 있는데 하나는 돼지나 소 등의 생체조직으로 만든 조직판막이고 다른 하나는 금속재질로 만든 기계판막이다. 이 두 판막은 서로 장단점이 있는데, 조직판막은 수명이 10년 정도로 짧은 단점이 있는 반면에 판막 주위에 혈액응고가 적어 항응고제 복용이 필요 없고, 손상이 서서히 일어난다. |
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| 영문 | valve | 한글 | 판막 |
|---|---|---|---|
| 설명 | 관 혹은 통로에 있는 막과 같은 주름. 내용물의 역류를 막는다. 1.심장판막: 우심방과 우심실사이의 삼첨판, 좌심방과 좌심실사이의 승모판, 우심실과 폐동맥사이의 폐동맥반월판, 좌심실과 대동맥사이의 대동맥반월판이 있다. 2.정맥판막: 정맥에서 발견되는 내막의 작은 첨 혹은 주름. 탄력성이 적어 역류되기 쉬운 정맥혈의 흐름을 역류없이 정상적인 방향으로 지속되도록 해준다. 3.인공판막: 심장판막부족이나 심장판막협착이 있어 더이상 자신의 판막으로는 생존이 불가능할 때 대신 이식하게 되는 인공판막을 말한다. 크게 동물의 조직을 이용한 것과 그렇지 않은 것으로 양분할 수 있다. 동물의 조직을 이용한 것은 주로 돼지나 소의 판막 또는 심외막 등을 이용하며, 그렇지 않은 것은 특수한 금속을 이용하여 만든다. |
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| PRAGMATIC | pregnancy, rheumatoid arthritis, acromegaly, glucose metabolism disorders, mechanical injury, amyloi... |
|---|---|
| DDRT | diseases, disorders and related topics |
| NINCDS/ADRDA | National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Rel... |
| ICD | I-cell disease; immune complex disease; implantable cardioverter defibrillator; impulse-control diso... |
| AVA | activity vector analysis; antiviral antibody; aortic valve area; aortic valve atresia; arteriovenous... |
| multiple drug resistant tuberculosis | A strain of TB that does not respond to two or more standard anti-TB drugs. MDR-TB usually occurs when treatment is interrupted thus allowing mutations in the organism to occur that confer drug resistance. (09 Oct 1997) |
|---|---|
| multiple ego states | Various psychological organizational state's reflecting different personas or life experiences. (05 Mar 2000) |
| multiple embolism | Embolism caused by the arrest of a number of small emboli. (05 Mar 2000) |
| multiple endocrine adenomatosis | The presence of functioning tumours in more than one endocrine gland, commonly the pancreatic islets and parathyroid glands, which may be associated with Zollinger-Ellison syndrome; dominant inheritance. Synonym: multiple endocrine adenomatosis. (05 Mar 2000) |
| multiple endocrine deficiency syndrome | <syndrome> Acquired deficiency of the function of several endocrine glands, usually on an auto-immune basis. Synonym: multiple glandular deficiency syndrome. (05 Mar 2000) |
| multiple endocrine neoplasia | (type I) This is a hereditary disorder in which two or more of the following glands: parathyroid, pancreas, pituitary, adrenals or thyroid develop hyperplasia or a tumour. (type II) This is a hereditary disorder in which two or more of the following glands: thyroid, adrenal or parathyroid, develop overgrowth (hyperplasia) or malignant cells (cancer). The underlying cause is genetic and a positive family history for this illness is a risk factor. Incidence: approximately 3 in 100,000 people in the general population. Origin: Gr. Plassein = to form (27 Sep 1997) |
| multiple endocrine neoplasia 1 | <radiology> Multiple endrocrine neoplasia syndrome three P's. Pituitary adenoma, 65% can develop Cushing's, acromegaly, prolactinoma, parathyroid hyperplasia / adenoma, 88% can develop hyper-PTH pancreatic isleT-cell tumour, gastrinoma (Z-E) most common, 50% of Z-E can develop MEN-1, inconstant features: bronchial/intestinal carcinoid, thyroid adenoma, adrenal cortical tumour, lipoma, thymoma tissue expression Primary hyperparathyroidism (90%), Gastrinoma (30%), Prolactinoma (15%), Other (10%). Synonym: Wermer syndrome (12 Dec 1998) |
| multiple endocrine neoplasia 2 | <radiology> Multiple endocrine neoplasia syndrome, medullary thyroid carcinoma, usually multifocal; metastasis to local nodes, lung, liver, usually calcify in liver, pheochromocytoma, almost always bilateral, parathyroid hyperplasia, may be secondary to calcitonin secreted by medullary thyroid carcinoma inconstant feature: adrenal cortical hyperplasia Synonym: Sipple syndrome (12 Dec 1998) |
| multiple endocrine neoplasia 3 | <radiology> Multiple endocrine neoplasia syndrome (type 2B, type 3), medullary thyroid carcinoma, pheochromocytoma, marfanoid habitus (Cf: Marfan syndrome), mucosal neuromas, neurofibromas, ganglioneuromatosis coli More info: MEN syndrome 2B Synonym: Schimke, marfanoid syndrome (12 Dec 1998) |
| multiple endocrine neoplasia type 1 | A rare syndrome characterised by hyperplasia and/or neoplasms of the pituitary, parathyroid glands, and pancreatic islets. Hyperparathyroidism occurs in 90% of the cases and is usually the first manifestation of the syndrome. The most frequent pancreatic manifestation is gastrinoma typically leading to zollinger-ellison syndrome. The appearance of this condition has been limited to the loss of allelic heterozygosity at the 11q13 locus on the long arm of chromosome 11. Patients overall exhibit long survival times. Chemotherapy is rare and surgical management is generally dependent on the genetic expression in individual patients. (12 Dec 1998) |
| multiple endocrine neoplasia type 2 | <syndrome> This is a hereditary disorder in which two or more of the following glands: thyroid, adrenal or parathyroid, develop overgrowth (hyperplasia) or malignant cells (cancer). The underlying cause is genetic and a positive family history for this illness is a risk factor. Incidence: approximately 3 in 100,000 people in the general population. (27 Sep 1997) |
| multiple endocrine neoplasia type 2a | A type of multiple endocrine neoplasia characterised by a virtually 100% incidence of medullary thyroid carcinoma, a 50% incidence of pheochromocytoma, and a lesser incidence of parathyroid adenomas associated with hyperparathyroidism. The condition is always transmitted through autosomal dominant inheritance. Genetic testing can identify individuals with the trait in early infancy. Treatment is usually excision of the enlarged parathyroid glands. (12 Dec 1998) |
| multiple endocrine neoplasia type 2b | A type of multiple endocrine neoplasia occurring as an isolated congenital presentation or as a distinct autosomal dominant disease. It is characterised by the 100% incidence of medullary thyroid carcinoma and frequent pheochromocytomas; patients seldom exhibit hyperparathyroidism. It is distinguished from men 2a by its characteristic physical appearance resulting from numerous neural defects including mucosal neuromas of the eyelids, lips, and tongue. The neural abnormalities also include widespread neurogangliomatosis of the gastrointestinal tract leading to abnormal gut motility. Treatment usually requires total thyroidectomy following evaluation for the presence of pheochromocytomas. (12 Dec 1998) |
| multiple epiphysial dysplasia | A dominantly inherited abnormality of epiphyses characterised by difficulty in walking, pain and stiffness of joints, stubby fingers, and often dwarfism of short-limb type; on X-ray examination, the epiphyses are mottled and irregular; ossification centres are late in appearance and may be multiple, but the vertebrae are normal. There is also an autosomal recessive form . Synonym: dysplasia epiphysialis multiplex. (05 Mar 2000) |
| multiple exostosis | A disturbance of enchondral bone growth in which multiple, generally benign osteochondromas of long bones appear during childhood, commonly with shortening of the radius and fibula; the ill-effects are usually mechanical but malignant change is rare; autosomal dominant inheritance. Synonym: diaphysial aclasis, hereditary deforming chondrodystrophy, multiple exostosis, osteochondromatosis. (05 Mar 2000) |