| cerebral sclerosis, diffuse | Diffuse progressive degeneration of the white matter of the brain, accompanied by mental deterioration, severe motor disturbances, and early death. (12 Dec 1998) |
|---|---|
| menstrual sclerosis | A slowly progressive sclerosis in the walls of the ovarian arteries which commences after puberty. Synonym: menstrual sclerosis, ovulational sclerosis. (05 Mar 2000) |
| physiologic sclerosis | A slowly progressive sclerosis in the walls of the ovarian arteries which commences after puberty. Synonym: menstrual sclerosis, ovulational sclerosis. (05 Mar 2000) |
| Monckeberg's sclerosis | Arterial sclerosis involving the peripheral arteries, especially of the legs of older people, with deposition of calcium in the medial coat (pipestem arteries) but with little or no encroachment on the lumen. Synonym: medial arteriosclerosis, Monckeberg's calcification, Monckeberg's degeneration, Monckeberg's medial calcification, Monckeberg's sclerosis. (05 Mar 2000) |
| combined sclerosis | A subacute or chronic disorder of the spinal cord, such as that occurring in certain patients with vitamin B12 deficiency, characterised by a slight to moderate degree of gliosis in association with spongiform degeneration of the posterior and lateral columns. Synonym: combined sclerosis, combined system disease, funicular myelitis, Putnam-Dana syndrome, vitamin B12 neuropathy. (05 Mar 2000) |
| posterior sclerosis | See Tabes dorsalis. (12 Dec 1998) |
| posterior spinal sclerosis | See Tabes dorsalis. (12 Dec 1998) |
| primary lateral sclerosis | Considered by many to be a subgroup of motor neuron disease; a slowly progressive degenerative disorder of the motor neurons of the cerebral cortex, resulting in widespread weakness on an upper motor neuron basis; spasticity, hyperreflexia, and Babinski signs are present, but not fasciculation potentials, nor any electrodiagnostic evidence of a lower motor neuron lesion. Synonym: lateral spinal sclerosis. (05 Mar 2000) |
| sclerosis | <pathology> A induration or hardening, especially hardening of a part from inflammation and in diseases of the interstitial substance. The term is used chiefly for such a hardening of the nervous system due to hyperplasia of the connective tissue or to designate hardening of the blood vessels. Origin: Gr. Sklerosis = hardness (18 Nov 1997) |
| sclerosis corii | <dermatology> Hardening of skin. (04 Mar 1998) |
| sclerosis cutanea | Synonym: scleroderma. (05 Mar 2000) |
| sclerosis of white matter | <radiology> Type of dysmyelinating disease, hereditary, peripheral nervous system unaffected in some disorders Specific diseases: adrenoleukodystrophy, metachromatic leukodystrophy, spongy degeneration (Canavan), globoid cell (Krabbe) leukodystrophy, Alexander disease, Pelizaeus-Merzbacher disease, Cockayne syndrome (12 Dec 1998) |
| hippocampal sclerosis | A loss of cortical neurons and a reactive astrocytosis in the hippocampal regions of some persons with epilepsy. (05 Mar 2000) |
| skin lesions of tuberous sclerosis | <radiology> Adenoma sebaceum, Shagreen patches, periungual fibromata, ash-leaf hypopigmentation (12 Dec 1998) |
| nodular sclerosis | <cardiology, pathology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |