| WHHHIMP | Wernicke encephalopathy/withdrawal, hypertensive encephalopathy, hypoglycemia, hypoxemia, intracrani... |
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| AMA | 1) Anti-Mitochondrial Antibodies 2) American Medical Association |
| GOTM | glutamic-oxaloacetic transaminase, mitochondrial |
| LIMM | lethal infantile mitochondrial myopathy |
| MA | malignant arrhythmia; management and administration; mandelic acid; masseter; Master of Arts; matern... |
| mitochondrial membrane | The double biomembrane surrounding the mitochondrion. (05 Mar 2000) |
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| mitochondrial myopathies | Diseases of the muscles characterised by morphologic changes in mitochondria and often associated with excessive lipid accumulation. Muscle biopsies reveal "the presence of overly abundant and large mitochondria (often containing abnormal inclusions and cristae) in many muscle fibres. The terms mitochondrial and lipid storage have been used interchangeably to designate these myopathies, since the enzymes essential for intramuscular lipid metabolism are contained in the mitochondria, and a defect in the latter results in an abnormal accumulation of lipid bodies in muscle fibres." often defects in various oxidative enzymes figure. One type of mitochondrial myopathy is called pleoconial with reference to "a remarkably large number (pleo-) of enlarged mitochondria in the biopsied muscle", another is "called megaconial with reference to giant (mega-) mitochondria in the muscle." (adams and victor: principles of neurology, 2d ed, p980-1) (12 Dec 1998) |
| mitochondrial oxidative damage endonuclease | <enzyme> An 8-oxog-specific DNA endonuclease from rat liver mitochondria; recognises and incises at 8-oxog and abasic acid sites in duplex DNA Registry number: EC 3.1.25.- Synonym: oxidative damage-specific endonuclease, mtode enzyme (26 Jun 1999) |
| mitochondrial sheath | The spirally arranged mitochondria in the middle piece of a spermatozoon; may control movement of the tail. (05 Mar 2000) |
| mitochondrial swelling | Increase in volume of mitochondria due to an influx of fluid; it occurs in hypotonic solutions due to osmotic pressure and in isotonic solutions as a result of altered permeability of the membranes of respiring mitochondria. (12 Dec 1998) |
| disease, mitochondrial | Mutations (changes) in the mitochondrial chromosome are responsible for a number of disorders including an eye disease (Leber's hereditary optic atrophy), a type of epilepsy (called MERRF which stands for Myoclonus Epilepsy with Ragged Red Fibres), and a cause of dementia (called MELAS for Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-like episodes). All mitochondrial diseases were entirely enigmatic before it was discovered that they were due to mutations not in regular chromosomes but the mitochondrial chromosome. (12 Dec 1998) |
| DNA, mitochondrial | Double-stranded DNA of mitochondria. In eukaryotes, the mitochondrial genome is circular and codes for ribosomal rnas, transfer rnas, and about 10 proteins. (12 Dec 1998) |
| alcoholic encephalopathy | <neurology> Encephalopathy associated with thiamin deficiency. Usually associated with chronic alcohol abuse. Other features include loss of memory and confabulation. Origin: Gr. Pathos = disease (27 Sep 1997) |
| bilirubin encephalopathy | <paediatrics> Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage. The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected, it is also called bilirubin encephalopathy. (12 Dec 1998) |
| Binswanger's encephalopathy | One of the causes of multiinfarct dementia, in which there are many infarcts and lacunes in the white matter, with relative sparing of the cortex and basal ganglia. Synonym: Binswanger's encephalopathy, encephalitis subcorticalis chronica, subcortical arteriosclerotic encephalopathy. (05 Mar 2000) |
| bovine spongiform encephalopathy | A new disease of cattle, first reported in 1986 in Great Britain, characterised clinically by apprehensive behaviour, hyperesthesia, and ataxia and histopathologically by spongiform changes in the gray-matter neuropil of the brain stem; it is thought to be caused by an agent, possibly a prion, similar to that observed as the cause of scrapie. Synonym: mad cow disease. (05 Mar 2000) |
| palindromic encephalopathy | A relatively mild form which tends to recur. (05 Mar 2000) |
| pancreatic encephalopathy | A metabolic encephalopathy associated with extensive pancreatic necrosis. (05 Mar 2000) |
| recurrent encephalopathy | A progressive form of encephalopathy occurring in young members of the same family; characterised by headache, vertigo, truncal ataxia, drowsiness and stupor, speech impairments, choreic-athetoid movements, and sometimes convulsions. (05 Mar 2000) |
| metabolic encephalopathy | Encephalopathy characterised by memory loss, vertigo, and generalised weakness, due to metabolic brain disease including hypoxia, ischemia, hypoglycaemia, or secondary to other organ failure such as liver or kidney. (05 Mar 2000) |