| metabolic coma | Coma resulting from diffuse failure of neuronal metabolism, caused by such abnormalities as intrinsic disorders of neuron or glial cell metabolism, or extracerebral disorders that produce intoxication or electrolyte imbalances. (05 Mar 2000) |
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| metabolic cooperation | <cell biology, molecular biology> Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids. Transfer is via channels constituted by the connexons of gap junctions and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radio labelled purines were transferred from wild type cells to mutants unable to utilise exogenous purines. (27 Jun 1999) |
| metabolic coupling | <cell biology, molecular biology> Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids. Transfer is via channels constituted by the connexons of gap junctions and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radio labelled purines were transferred from wild type cells to mutants unable to utilise exogenous purines. (27 Jun 1999) |
| metabolic craniopathy | <syndrome> Hyperostosis frontalis interna in elderly women, with obesity and neuropsychiatric disorders of uncertain cause; at least sometimes familial. Synonym: metabolic craniopathy, Stewart-Morel syndrome. (05 Mar 2000) |
| metabolic detoxication, drug | Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes those metabolic transformations that make the substance more soluble for faster renal excretion. (12 Dec 1998) |
| metabolic disease | Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (metabolism, inborn errors) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (12 Dec 1998) |
| metabolic encephalopathy | Encephalopathy characterised by memory loss, vertigo, and generalised weakness, due to metabolic brain disease including hypoxia, ischemia, hypoglycaemia, or secondary to other organ failure such as liver or kidney. (05 Mar 2000) |
| metabolic equivalent | The oxygen cost of energy expenditure measured at supine rest (1 MET = 3.5 ml O2 per kg of body weight per minute); multiples of MET are used to estimate the oxygen cost of activity, e.g., 3 to 5 METs for light work; more than 9 METs for heavy work. (05 Mar 2000) |
| metabolic indican | 1. <chemistry> A glucoside obtained from woad (indigo plant) and other plants, as a yellow or light brown sirup. It has a nauseous bitter taste, a decomposes or drying. By the action of acids, ferments, etc, it breaks down into sugar and indigo. It is the source of natural indigo. 2. <physiology> An indigo-forming substance, found in urine, and other animal fluids, and convertible into red and blue indigo (urrhodin and uroglaucin). Chemically, it is indoxyl sulphate of potash, C8H6NSO4K, and is derived from the indol formed in the alimentary canal. Synonym: uroxanthin. See: Indigo. Source: Websters Dictionary (01 Mar 1998) |
| metabolic mucinosis | Diffuse or pretibial myxoedema, lichen myxoedematosus, gargoylism, secondary mucinosis, degeneration in tumours, localised mucinosis, follicular, papular, plaque-like, focal, and myxoid or synovial cyst. Origin: mucin + G. -osis, condition (05 Mar 2000) |
| metabolic pool | The quantity of a given chemical compound or group of related compounds participating in metabolic reactions; may constitute only a portion of the total bodily content of such compounds. (05 Mar 2000) |
| metabolimeter | A modified calorimeter for measuring the rate of basal metabolism. (05 Mar 2000) |
| metabolin | <biochemistry> Any substance produced by metabolism or by a metabolic process. (18 Nov 1997) |
| metabolisation | <biochemistry> The chemical process by which matter is broken down into simpler substances, said especially of food processed by the human body. (18 Nov 1997) |
| metabolise | To undergo the chemical changes of metabolism. (05 Mar 2000) |