| muscarinic acetylcholine receptor | Distinct from the nicotinic ACh receptor in having no intrinsic ion channel, the receptor is formed from one protein chain with 7 transmembrane regions. The receptors produce their effect via activation of GTP-binding proteins. (18 Nov 1997) |
|---|---|
| muscarinic agonist | Drugs that bind to and activate muscarinic cholinergic receptors (receptors, muscarinic). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate. (12 Dec 1998) |
| muscarinic antagonist | Drugs which bind with muscarinic cholinergic receptors but do not activate them, thus preventing access to acetylcholine; examples include atropine, scopolamine, propantheline, and pirenzepine. (05 Mar 2000) |
| muscarinic antagonists | Drugs that bind to but do not activate muscarinic cholinergic receptors (receptors, muscarinic), thereby blocking the actions of endogenous acetycholine or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. Antagonists that discriminate among the various muscarinic receptor subtypes and might allow better control of peripheral and central actions are under development. (12 Dec 1998) |
| muscarinic receptor kinase | <enzyme> Phosphorylates muscarinic acetylcholine receptors and beta-adrenergic receptors Registry number: EC 2.7.- Synonym: muscarinic acetylcholine receptor kinase, machr kinase (26 Jun 1999) |
| muscarinic receptors | Membrane-bound proteins whose extracellular domain contains a recognition site for acetylcholine (ACh); combination of Ach with the receptor initiates a physiologic change (slowing of heart rate, increased glandular secretory activity and stimulation of smooth muscle contractions); changes are observed after treatment with the mushroom alkaloid, muscarine. Muscarinic receptors are to be distinguished from nicotinic receptors. (05 Mar 2000) |
| muscarinism | Mushroom poisoning, characterised by gastrointestinal upset, liver andkidney damage, central nervous system effects and damage, and possiblydeath. (09 Oct 1997) |
| muscat | <botany> A name given to several varieties of Old World grapes, differing in colour, size, etc, but all having a somewhat musky flavor. The muscat of Alexandria is a large oval grape of a pale amber colour. Alternative forms: muskat. Origin: F. See Muscadel. Source: Websters Dictionary (01 Mar 1998) |
| muschelkalk | <geology> A kind of shell limestone, whose strata form the middle one of the three divisions of the Triassic formation in Germany. See Chart, under Geology. Origin: G, from muschel shell + kalk limestone. Source: Websters Dictionary (01 Mar 1998) |
| musci | <botany> An order or subclass of cryptogamous plants; the mosses. See Moss, and Cryptogamia. Origin: L. Muscus moss. Source: Websters Dictionary (01 Mar 1998) |
| muscicapine | <ornithology> Of or pertaining to the Muscicapidae, a family of birds that includes the true flycatchers. Origin: L. Musca a fly + capere to catch. Source: Websters Dictionary (01 Mar 1998) |
| muscicide | An agent destructive to flies. Origin: L. Musca, fly, + caedo, to kill (05 Mar 2000) |
| muscidae | A family of the order diptera with over 700 species. The genera are musca domesticus (houseflies), musca autumnalis (face fly), stomoxys (stable fly), haematobia (horn fly), glossina spp. (tsetse flies), and fannia. Both sexes of the stable fly, horn fly and tsetse fly bite. (12 Dec 1998) |
| musciform | <zoology> Having the form or structure of flies of the genus Musca, or family Muscidae. Origin: Musca. <botany> Having the appearance or form of a moss. Origin: Muscus. Source: Websters Dictionary (01 Mar 1998) |
| muscimol | <chemical> 5-(aminomethyl)-3-isoxazolol. Neurotoxic isoxazole isolated from amanita muscaria and a. Phalloides and also obtained by decarboxylation of ibotenic acid. It is a potent agonist at gaba-a receptors and is used mainly as an experimental tool in animal and tissue studies. Pharmacological action: gaba agonists. Chemical name: 3(2H)-Isoxazolone, 5-(aminomethyl)- (12 Dec 1998) |