| duffy blood-group system | A blood group consisting mainly of the antigens fy(a) and fy(b), determined by allelic genes, the frequency of which varies profoundly in different races; amorphic genes are common. (12 Dec 1998) |
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| I blood-group system | A blood group related both to the abo and p systems that includes several different antigens found in most people on erythrocytes, in milk, and in saliva. The antibodies react only at low temperatures. (12 Dec 1998) |
| K blood group | K blood group See Kell blood group, Blood Groups appendix. (05 Mar 2000) |
| Kell blood group | <haematology, immunology> Blood type classification based on a group of erythrocyte antigens that is characterised by an antibody called anti-K. Multiple erythrocytic antigens that comprise at least three pairs of alternates and amorphs, determined by one complex gene or possibly several genes at closely linked loci. The system is important in transfusion reactions. Its expression involves the X chromosome. (21 Jun 2000) |
| Kidd blood group | See Blood Groups appendix. (05 Mar 2000) |
| kidd blood-group system | A group of antigens consisting principally of jk(a) and jk(b), determined by allelic genes. Amorphs are encountered. Antibodies of these substances are usually weak and quite labile, stimulated by erythrocytes. (12 Dec 1998) |
| Lewis blood group | <haematology> A pair of blood group activities associated with the A, B, H substances. Lewis Lea is a separate gene, whereas Leb arises from the combined activity of the enzymes specified by Le(a) and H genes. (18 Nov 1997) |
| lewis blood-group system | A group of dominantly and independently inherited antigens associated with the abo blood factors. They are glycolipids present in plasma and secretions that may adhere to the erythrocytes. The phenotype le(b) is the result of the interaction of the le gene le(a) with the genes for the abo blood groups. (12 Dec 1998) |
| lutheran blood-group system | A complex blood group system having pairs of alternate antigens and amorphic genes, but also subject to a dominant independently segregating repressor. (12 Dec 1998) |
| ABO antigens | <haematology, immunology> A system of genetically determined antigens (proteins) located on the surface of the erythrocyte. The presence of these specific antigens gives a blood its unique properties. Because of the antigen differences existing between individuals, blood groups are significant in blood transfusions, maternal-foetal incompatibilities (erythroblastosis foetalis), tissue and organ transplantation. (27 Sep 1997) |
| Am antigens | Allotypic determinants (antigens) on human immunoglobulin alpha heavy chains. (05 Mar 2000) |
| antigens | Substances which are capable, under appropriate conditions, of inducing a specific immune response and of reacting with the products of that response, that is, with specific antibodies or specifically sensitised T-lymphocytes, or both. Antigens may be soluble substances, such as toxins and foreign proteins, or particulates, such as bacteria and tissue cells; however, only the portion of the protein or polysaccharide molecule known as the antigenic determinant (epitopes) combines with antibody or a specific receptor on a lymphocyte. (12 Dec 1998) |
| antigens, archaeal | Substances of archaeal origin that have antigenic activity. (12 Dec 1998) |
| antigens, bacterial | Substances elaborated by bacteria that have antigenic activity. (12 Dec 1998) |
| antigens, CD | <immunology> Differentiation antigens residing on human leukocytes. CD stands for cluster of differentiation, which refers to groups of monoclonal antibodies that show similiar reactivity with certain subpopulations of antigens. The subpopulations of antigens are also known by the same CD designation. (12 Dec 1998) |