| MIBG scintiscan | <investigation, radiology> A nuclear scan that images the adrenal glands after a radioactive tracer is injected into the bloodstream. This test is useful in detecting a pheochromocytoma, particularly if it not within the adrenal gland. (12 Jan 1998) |
|---|---|
| MIC | <abbreviation> Minimal inhibitory concentration. (05 Mar 2000) |
| mica | <chemical> The name of a group of minerals characterised by highly perfect cleavage, so that they readily separate into very thin leaves, more or less elastic. They differ widely in composition, and vary in colour from pale brown or yellow to green or black. The transparent forms are used in lanterns, the doors of stoves, etc, being popularly called isinglass. Formerly called also cat-silver, and glimmer. The important species of the mica group are: muscovite, common or potash mica, pale brown or green, often silvery, including damourite (also called hydromica); biotite, iron-magnesia mica, dark brown, green, or black; lepidomelane, iron, mica, black; phlogopite, magnesia mica, colourless, yellow, brown; lepidolite, lithia mica, rose-red, lilac. Mica (usually muscovite, also biotite) is an essential constituent of granite, gneiss, and mica slate; biotite is common in many eruptive rocks; phlogopite in crystalline limestone and serpentine. Mica diorite, a schistose rock, consisting of mica and quartz with, usually, some feldspar. Origin: L. Mica crumb, grain, particle; cf. F. Mica. Source: Websters Dictionary (01 Mar 1998) |
| micaceo-calcareous | <geology> Partaking of the nature of, or consisting of, mica and lime; applied to a mica schist containing carbonate of lime. Source: Websters Dictionary (01 Mar 1998) |
| micatosis | Pneumoconiosis due to inhalation of mica particles. (05 Mar 2000) |
| mice | The common name for the species mus musculus. (12 Dec 1998) |
| mice minute virus | The type species of parvovirus prevalent in mouse colonies and found as a contaminant of many transplanted tumours or leukaemias. (12 Dec 1998) |
| mice, inbred cftr | A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the cftr (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands. (12 Dec 1998) |
| mice, inbred hrs | Homozygous, permanently near-hairless mice which lose their hair at about 10 days of age. (12 Dec 1998) |
| mice, inbred mdx | A strain of mice arising from a spontaneous mutation (mdx) in inbred c57bl mice. This mutation is x chromosome-linked and produces viable homozygous animals that lack the muscle protein dystrophin, have high serum levels of muscle enzymes, and possess histological lesions similar to human muscular dystrophy. The histological features, linkage, and map position of mdx make these mice a worthy animal model of duchenne muscular dystrophy. (12 Dec 1998) |
| mice, inbred mrl lpr | A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the mrl/lpr is a useful model to study behavioural and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents. (12 Dec 1998) |
| mice, inbred nod | A strain of non-obese diabetic mice developed in japan that has been widely studied as a model for T-cell-dependent autoimmune insulin-dependent diabetes mellitus in which insulitis is a major histopathologic feature, and in which genetic susceptibility is strongly MHC-linked. (12 Dec 1998) |
| mice, inbred sencar | Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to uv radiation tumourigenesis with single high-dose, but not chronic low-dose, exposures. Sencar (sensitive to carcinogenesis) mice are used in research as an animal model for tumour production. (12 Dec 1998) |
| mice, inbred strains | Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation. (12 Dec 1998) |
| mice, jimpy | Myelin-deficient mutants which are from the inbred tabby-jimpy strain. (12 Dec 1998) |