| adult pseudohypertrophic muscular dystrophy | Muscular dystrophy of late onset, often in the second or third decade, with relatively mild course; X-linked recessive inheritance; perhaps allelic with Duchenne's dystrophy, but milder and not a genetic lethal. Compare: Duchenne dystrophy. Synonym: Becker type tardive muscular dystrophy. (05 Mar 2000) |
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| adult respiratory distress syndrome | <chest medicine, syndrome> A clinical syndrome that includes pulmonary insufficiency. It is a descriptive term that is applied to a variety of diffuse infiltrative processes in the lung. Manifestations include severe shortness of breath, rapid breathing and arterial hypoxaemia (low oxygen). Chest X-ray shows bilateral diffuse infiltrates. Treatment most often includes mechanical respiratory support. Causes include toxic gas (chlorine, NO2, smoke) exposure, severe metabolic derangement, gastric acid aspiration, pancreatitis, sepsis and trauma. Acronym: ARDS (12 Jul 2000) |
| adult rickets | <pathology> A condition marked by softening of the bones (due to impaired mineralisation, with excess accumulation of osteoid), with pain, tenderness, muscular weakness, anorexia and loss of weight, resulting from deficiency of vitamin D and calcium. Origin: Gr. Malakia = softness (18 Nov 1997) |
| adult T-cell leukaemia | Lymph nodes show a mixture of small and large atypical cells which are polymorphic and express nuclear pleiomorphism. Adult T-cell leukaemia is caused by HTLV-1 and is rare in the US and Europe but common in Japan. Tumour cells express CD2, CD3, CD5 and lack CD7. The most common chromosome change reported in adult T-cell leukaemia is presence of the 14q + marker (05 Mar 2000) |
| adult T-cell lymphoma | <tumour> An acute or subacute disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcaemia. Synonym: adult T-cell leukaemia. (05 Mar 2000) |
| adult tuberculosis | Tuberculosis found in adults and characterised by lesions near the apex of an upper lobe, which may cavitate or heal with scarring without spreading to lymph nodes; theoretically, secondary tuberculosis may be due to exogenous reinfection or to reactivation of a dormant endogenous infection. Synonym: adult tuberculosis, postprimary tuberculosis, reinfection tuberculosis. (05 Mar 2000) |
| respiratory distress syndrome, adult | A syndrome of life-threatening progressive pulmonary insufficiency in the absence of known pulmonary disease, usually following a systemic insult such as surgery or major trauma. (12 Dec 1998) |
| coeliac disease, adult | See Coeliac sprue. (12 Dec 1998) |
| still's disease, adult-onset | Systemic-onset rheumatoid arthritis in adults. It differs from classical rheumatoid arthritis in that it is more often marked by acute febrile onset, and generalised lymphadenopathy and hepatosplenomegaly are more prominent. (12 Dec 1998) |
| disease, adult coeliac | This condition results from an immune (allergic) reaction to gluten, a protein found in wheat and related grains and present in many foods that we eat. Sprue causes impaired absorption and digestion of nutrients through the small intestine. Symptoms include requent diarrhoea and weight loss. A skin condition called dermatitis herpetiformis can be associated with coeliac sprue. The most accurate diagnostic test for sprue is a biopsy of the involved small bowel. Treatment is to avoid gluten in the diet. Medications are used for refractory (stubborn) sprue. Known under a number of other names, including coeliac sprue. (12 Dec 1998) |
| anterior region of leg | The anterior surface of the inferior limb between the knee and the ankle. Synonym: facies cruralis anterior, regio cruralis anterior, anterior crural region, anterior surface of leg, facies anterior cruris. (05 Mar 2000) |
| bandy-leg | A deformity marked by medial angulation of the leg in relation to the thigh; an outward bowing of the legs. Synonym: bandy-leg, bowleg, bow-leg, tibia vara. (05 Mar 2000) |
| Barbados leg | <medicine> A disease of the skin, in which it become enormously thickened, and is rough, hard, and fissured, like an elephant's hide. Origin: L, fr. Gr, from, an elephant. Source: Websters Dictionary (01 Mar 1998) |
| bow-leg | A deformity marked by medial angulation of the leg in relation to the thigh; an outward bowing of the legs. Synonym: bandy-leg, bowleg, bow-leg, tibia vara. (05 Mar 2000) |
| medial cutaneous nerve of leg | <anatomy, nerve> Arises from the tibial in the popliteal space, passes down the calf between the two heads of the gastrocnemius and unites in the middle of the leg with the communicating branch of the common peroneal to form the sural nerve, distributed to the skin of the distal and lateral surfaces of the leg and ankle. Synonym: nervus cutaneus surae medialis, medial cutaneous nerve of leg, popliteal communicating nerve, tibial communicating nerve. (05 Mar 2000) |