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mucous plaque In dentistry, a mass of filamentous microorganisms and large variety of smaller forms attached to the surface of a tooth which, depending on bacterial activity and environmental factors, may give rise to caries, calculus, or inflammatory changes in adjacent tissue.
Synonym: dental plaque, mucous plaque, mucinous plaque.
(05 Mar 2000)
pleural plaque Fibrous thickening of the parietal pleura, characteristically caused by inhalation exposure to asbestos.
(05 Mar 2000)
haemolytic plaque assay <investigation> A haemolytic plaque assay is a lab technique used to show that certain antibodies are secreted by antibody-making cells when these cells are mixed with red blood cells.
The mixture is spread onto a plate of agar, if a plaque appears, it means that the red blood cells have been destroyed (by haemolysis) by the antibodies.
(09 Oct 1997)
senile plaque <neurology> Characteristic feature of the brains of Alzheimer's patients and aged monkeys, consisting of a core of amyloid fibrils surrounded by dystrophic neurites.
The principal component of amyloid fibrils in senile plaques is B/A4, a peptide of about 4 kD that is derived from the larger amyloid precursor protein (APP). The B/A4 sequence is located near the C terminus of APP.
(18 Nov 1997)
neuritic plaque <cell biology> Abnormal cluster of dead and dying nerve cells, other brain cells and protein.
Neuritic plaques are one of the characteristic structural abnormalities found in the brains of alzheimer patients. Upon autopsy, the presence of neuritic plaques andneurofibrillary tangles is used to positively diagnose Alzheimer's disease.
(22 May 1997)
dental plaque <dentistry> A soft, thin film of food debris, mucin and dead epithelial cells deposited on the teeth, providing the medium for the growth of various bacteria.
The main inorganic components are calcium and phosphorus with small amounts of magnesium, potassium and sodium, the organic matrix consists of polysaccharides, proteins, carbohydrates, lipids and other components.
Plaque plays an important aetiological role in the development of dental caries and periodontal and gingival diseases and provides the base for the development of materia alba, calcified plaque forms dental calculus.
(19 Mar 1998)
dental plaque index An index which scores the degree of dental plaque accumulation.
(12 Dec 1998)
fibrous plaque Thickened area of arterial intima with accumulation of smooth muscle cells and fibrous tissue (collagen etc.) produced by the fat laden smooth muscle cells. Below the thickening may be free extracellular lipid and debris that, if much necrosis is also present, is referred to as an atheroma.
(18 Nov 1997)
anaplastic large cell lymphoma <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2).
Synonym: Ki-1+ lymphoma.
(05 Mar 2000)
bilateral large kidneys <radiology> Autosomal dominant (adult) polycystic disease, lymphoma Cf: other urographic patterns
(12 Dec 1998)
carcinoma, large cell A tumour of undifferentiated (anaplastic) cells of large size. It is usually bronchogenic.
(12 Dec 1998)
papillary adenoma of large intestine <tumour> Appears as a solitary sessile, often large, tumour of colonic mucosa composed of mucinous epithelium covering delicate vascular projections; malignant change occurs frequently; hypersecretion occurs rarely. Also known as adenoma.
Synonym: papillary adenoma of large intestine.
(05 Mar 2000)
ribulose-1,5-bisphosphate carboxylase-oxygenase large subunit epsilonN-methyltransferase <enzyme> An aspect of EC 2.1.1.43; trimethylates lys-14 of rubisco
Registry number: EC 2.1.1.-
Synonym: rubisco lsmt, rubisco large subunit lysine n-methyltransferase
(26 Jun 1999)
the large mass of the telencephalon On either side of the midline, consisting of the cerebral cortex and its associated fibre systems, together with the deeper-lying subcortical telencephalic nuclei (i.e., basal ganglia [nuclei]).
(05 Mar 2000)
unilateral large kidney <radiology> Multifocal: xanthogranulomatous pyelonephritis (XGP), malakoplakia, multicystic dysplastic kidney Cf: other urographic patterns
smooth kidney: renal vein thrombosis, acute arterial infarction, obstructive uropathy, acute bacterial nephritis, compensatory hypertrophy, duplicated pelvocalyceal system Cf: other urographic patterns
multifocal: solid neoplastic mass, malignant, adenocarcinoma, adult nephroblastoma, invasive transitional cell carcinoma, sarcoma, metastasis, benign, hamartoma, adenoma, mesenchymal tumour cystic mass, simple cyst, focal hydronephrosis, multilocular cystic nephroma, arteriovenous malformation Cf: other urographic patterns
(12 Dec 1998)
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