| langerhans cell | Paul langerhans, german pathologist, 1847-1888 1. Star-shaped cells in the deeper portions of the germinative layer of the epidermis. 2. Irregulare wandering cells in the intercellular spaces of rhe cornea. Synonym: Langerhans stellate corpuscles. (16 Dec 1997) |
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| langerhans cell histiocytoses | An immunologic disorder of unknown cause where there is proliferation of histiocytes (a type of cell in the immune system) in the bloodstream. The disorder is characterised by inflammation of the bronchioles and small pulmonary vessels that leads to fibrosis and destruction of alveolar cell walls. Cigarette smoking is considered a risk factor. Individuals with this disorder are also at increased risk for spontaneous pneumothorax. Symptoms include cough, chest pains, shortness of breath, fever, weight loss and malaise. Bronchoscopy with biopsy confirms the diagnosis. Childhood forms exist and cause more systemic symptoms and findings such as failure to thrive, weight loss, fevers, irritability, rash and bone pains. Treatment is with corticosteroids. (27 Sep 1997) |
| langerhans cells | Recirculating, dendritic, antigen-presenting cells containing characteristic racket-shaped granules (birbeck granules). They are found principally in the stratum spinosum of the epidermis and are rich in class II major histocompatibility complex molecules. (12 Dec 1998) |
| Langerhans' cells | Dendritic clear cell's in the epidermis, containing distinctive granules that appear rod-or racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are believed to be antigen fixing and processing cell's of monocytic origin; active participants in cutaneous delayed hypersensitivity. (05 Mar 2000) |
| Langerhans' granule | A small tennis racket-shaped membrane-bound granule with characteristic cross-striated internal ultrastructure; first reported in Langerhans' cells of the epidermis. Synonym: Birbeck's granule. (05 Mar 2000) |
| Langerhans' islands | <anatomy> Groups of cells found within the pancreas: A cells and B-cells secrete insulin and glucagon. See: D cells. (18 Nov 1997) |
| Langerhans, Paul | <person> B. Berlin, July 25th, 1847. Was a Physician and an Anatomist and became Professor of Pathological Anatomy in Freiburg. On his retirement went to Madeira. D. Funchal, July 20th, 1888. Islets of Langerhans - collection of cells in the pancreas which produce insulin and glucagon. Cells of Langerhans - dendritic cells found in the epidermis of the skin. Lived: 1847-1888. (05 Dec 1998) |
| Langenbeck a. |
amputation in which the flaps are cut from without inward.
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| Langenbeck amputation, flap, triangle |
see under amputation, flap, and triangle.
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| Langenbeck pedicle mucoperiosteal f. |
von Langenbeck bipedicle mucoperiosteal f.
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| Langenbeck's t. |
one having its apex at the anterior superior spine of the ilium, its base along the anatomical neck of the femur, and its external side by the external face of the great trochanter of the femur.
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| Langer's axillary a. |
axillary a.
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