| lupuline | <chemistry> An alkaloid extracted from hops as a colourless volatile liquid. Origin: NL. Lupulus the hop, fr. L. Lupus the hop: cf. F. Lupuline. Source: Websters Dictionary (01 Mar 1998) |
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| lupulinic | <chemistry> Pertaining to, or obtained from, hops; specifically, designating an acid obtained by the decomposition of lupulin. Source: Websters Dictionary (01 Mar 1998) |
| lupus | A systemic disease that results from an autoimmune mechanism. Individuals with lupus will produce antibodies to their own body tissues. The resultant inflammation can cause kidney damage, arthritis, pericarditis and vasculitis. (27 Sep 1997) |
| lupus anticoagulant | An immunoglobulin that interferes with blood coagulation and has antithromboplastin activity. This immunoglobulin can prolong blood clotting and occurs in approximately 25% of people with lupus. (27 Sep 1997) |
| lupus anticoagulants | Lupus anticoagulants are a common cause of a prolonged activated partial thromboplastin time (APTT) which is corrected by the addition of platelet -rich plasma (or phospholipids) and not by platelet-poor plasma. The methods of choice for detection of lupus anticoagulants are the kaolin clotting time using the rabbit brain neutralisation procedure and the dilute Russell viper venom test (dRVVT). Current data suggest that lupus anticoagulants and antibodies to negatively charged phospholipids (cardiolipin, phosphatidylserine, phosphatidic acid and phosphatidylinositol) are risk factors for arterial and venous thrombosis and for recurrent abortions in populations of patients which are distinct but overlapping. Drug-induced lupus anticoagulants are also associated with increased risk of thrombosis. Current testing for lupus anticoagulants and phospholipid antibodies (cardiolipin plus phosphatidylserine) may be useful for assessing risk in patients with systemic lupus erythematosus. Some data indicate that lupus anticoagulants assays are more reliable predictors of thrombosis, foetal loss and thrombocytopenia than are cardiolipin antibody (ACA) assays. Although the technology is in many ways more reliable, the rush to describe associations of lupus anticoagulants with various disorders has been much less scientifically unseemly than has been that of ACAs with their bewildering variety of clinical associations. The contribution of one serious study must, it seems, render tolerable the excess of trivia recently published in this area. See also cardiolipin antibodies and phospholipid antibodies. (05 Mar 2000) |
| lupus band test | A direct immunofluorescent technique for demonstrating a band of immunoglobulins at the dermal-epidermal junction of the skin of patients with lupus erythematosus. (05 Mar 2000) |
| lupus coagulation inhibitor | An antiphospholipid antibody found in association with systemic lupus erythematosus (lupus erythematosus, systemic), antiphospholipid syndrome, and in a variety of other diseases as well as in healthy individuals. In vitro, the antibody interferes with the conversion of prothrombin to thrombin and prolongs the partial thromboplastin time. In vivo, it exerts a procoagulant effect resulting in thrombosis mainly in the larger veins and arteries. It further causes obstetrical complications, including foetal death and spontaneous abortion, as well as a variety of haematologic and neurologic complications. (12 Dec 1998) |
| lupus erythematodes | Skin disease in which there are red scaly patches, especially over the nose and cheeks. May be a symptom of systemic lupus erythematosus. (18 Nov 1997) |
| lupus erythematosus | Skin disease in which there are red scaly patches, especially over the nose and cheeks. May be a symptom of systemic lupus erythematosus. (18 Nov 1997) |
| lupus erythematosus cell | <pathology> Phagocyte that has ingested nuclear material of another cell: characteristic of systemic lupus erythematosus. (18 Nov 1997) |
| lupus erythematosus cell test | <investigation> A test for lupus that measures the presence of autoantibodies against nuclear proteins in the blood. Performed on a normal venipuncture specimen, this test is positive in 70 to 80% of patients with lupus. Some patients with rheumatoid arthritis, scleroderma and drug-induced lupus may also have a positive test result. (27 Sep 1997) |
| lupus erythematosus profundus | A subcutaneous panniculitis with marked lymphocyte infiltration of fat lobules giving rise to deep-seated, firm, rubbery nodules that sometimes become ulcerated, usually of the face; may occur in systemic and localised lupus erythematosus. Synonym: lupus profundus. (05 Mar 2000) |
| lupus erythematosus test | <investigation> A test for lupus that measures the presence of autoantibodies against nuclear proteins in the blood. Performed on a normal venipuncture specimen, this test is positive in 70 to 80% of patients with lupus. Some patients with rheumatoid arthritis, scleroderma and drug-induced lupus may also have a positive test result. (27 Sep 1997) |
| lupus erythematosus, cutaneous | A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= lupus erythematosus, systemic with skin lesions), subacute, and chronic (= lupus erythematosus, discoid). (12 Dec 1998) |
| lupus erythematosus, discoid | A chronic form of cutaneous lupus erythematosus (lupus erythematosus, cutaneous) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterised by the presence of discoid skin plaques showing varying degrees of oedema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur. (12 Dec 1998) |
Synonyms : Systemic Lupus Erythematosus, Disease, Libman-Sacks, Libman Sacks Disease
Synonyms : Glomerulonephritides, Lupus, Lupus Glomerulonephritides, Lupus Nephritides, Nephritides, Lupus
Synonyms : Central Nervous System Lupus, Central Nervous System Systemic Lupus Erythematosis, Lupus Meningoencephalitis, Systemic Lupus Erythematosis, Central Nervous System, Lupus Meningoencephalitides, Meningoencephalitides, Lupus, Meningoencephalitis, Lupus
| lupus |
A chronic inflammatory connective tissue disease marked by skin rashes, joint pain and swelling, inflammation of the kidneys, inflammation of the fibrous tissue surrounding the heart (ie, the pericardium), as well as other problems. Not all affected individuals display all of these problems. Also called systemic lupus erythematosus.
출처: www.stjude.org/glossary
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| lupus |
Any of various chronic skin conditions characterized by ulcerative lesions that spread over the body. No longer in scientific use. [Webster]
출처: www.antiquusmorbus.com/English/EnglishL.htm
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| lupus |
Also known as systemic lupus erythematosus (SLE). Lupus is a chronic inflammatory condition caused by an autoimmune disease. An autoimmune disease occurs when the body's tissues are attacked by its own immune system. Individuals with lupus have unusual antibodies in their blood that are targeted against their own body tissues.
출처: www.nutrabio.com/Definitions/definitions_l.htm
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| lupus |
A systemic disease that results from an autoimmune mechanism. Individuals with lupus will produce antibodies to their own body tissues. The resultant inflammation can cause kidney damage, arthritis, pericarditis and vasculitis.
출처: virtualtrials.com/dictionary.cfm
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| lupus anticoagulant |
An antibody first noted in the disease systemic lupus erythematosus or
출처: www.jansen.com.au/Dictionary_JL.html
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| LUP | a chronic inflammatory collagen disease affecting connective tissue (skin or joints) |
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| LUP | tuberculosis of the skin |