| LOC | a permanent department created to perform the work of a local government |
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| LOC | the government of a local area |
| LOC | freedom of a local government to determine by popular vote the applicability of a controversial law in their jurisdiction |
| LOC | an oscillator whose output heterodynes with the incoming radio signal to produce sum and difference tones |
| LOC | a local branch of the Post Office Department |
| LOC | the official time in a local region (adjusted for location around the Earth) |
| LOC | the scene of any event or action (especially the place of a meeting) |
| LOC | a determination of the location of something |
| LOC | (physiology) the principle that specific functions have relatively circumscribed locations in some particular part or organ of the body |
| LOC | (physiology) the principle that specific functions have relatively circumscribed locations in some particular part or organ of the body |
| LOC | (physiology) the principle that specific functions have relatively circumscribed locations in some particular part or organ of the body |
| LOC | locate |