| 영문 | influenza virus | 한글 | 인플루엔자바이러스 |
|---|---|---|---|
| 설명 | 인플루엔자의 병원체. 상기도 점막에 침입하여 호흡기 질환을 일으킨다. 보체 결합 항원의 차이에 따라 A-B-C 세형태로 나뉘며, 유행할 때마다 혈구 응집 항원이 변이하여 광범위한 유행을 나타낸다. 껍질이 있는 80~150nm의 공모양, 나선 대칭 RNA 바이러스이다. 두 종류의 스파이크, 뉴라미니다아제(neuraminidase, NA), 당단백질과 헤마글루티닌(hemagglution, HA) 당단백질을 만든다. A형의 NA에는 N1-N2의 두 종류, HA에는 HAO-HA1-HA2-HA3의 네 종류가 있다. A형은 말-돼지-새에 감염하며 새로운 아형은 동물 바이러스와의 조환형이며, 그 밖에 동일 아형내 점변이가 있다. B, C형은 사람 이외에는 감염되지 않는다. 닭의 적혈구를 응집하는 성질이 있다. 바이러스 진단에는 환자의 인두 세척액에서 분리한다든가, 또는 환자의 혈청항체에 의한 특이적 적혈구 응집저지검사, 뉴라미니다아제 활성저지검사 또는 중화검사 등으로 검출한다. |
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| rough strain | <microbiology> Bacterial strains that have altered outer cell wall carbohydrate chains causing colonies on agar to change their appearance from smooth to dull. In Streptococci the smooth strains are virulent whereas the rough strains are not. This is partly because the rough strains are much more readily phagocytosed. (17 Dec 1997) |
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| wild strain | <virology> A viral strain found naturally, as opposed to one created in the laboratory. (09 Oct 1997) |
| wild-type strain | A strain found in nature or a standard strain. See: auxotrophic strains, prototrophic strains. (05 Mar 2000) |
| congenic strain | An inbred strain of animals produced by continued crossing of a gene of one line onto another inbred (isogenic) line. (05 Mar 2000) |
| muscle strain | An acute tearing injury to muscle. Usually associated with a small amount of bleeding (haematoma) into the injured muscle tissue. (27 Sep 1997) |
| crippled strain | <microbiology> A strain of bacteria, typically highly pathogenic, that has been genetically engineered so that it cannot survive on anything but a veryspecialised medium of nutrients, this is done so that geneticists can experiment on certain pathogens without the risk that they will escape fromthe lab. (09 Oct 1997) |
| HFR strain | A strain, or clone, in which a conjugative plasmid (such as an F'), integrated in the bacterial genome, is instrumental in the transfer (along with plasmid DNA) of integrated bacterial DNA in a sequential manner to a suitable recipient. Origin: high freguency of recombination (05 Mar 2000) |
| pseudolysogenic strain | A bacterial strain that is contaminated with a bacteriophage of low infectivity. Synonym: pseudolysogenic strain. (05 Mar 2000) |
| high frequency recombination strain | A type of bacterial strain which is able to pass on genetic information to neighboring bacteria at a high rate. The high-frequency recombination strain (Hfr) is able to do this because it possesses the f plasmid and can therefore initiate bacterial conjugation. (09 Oct 1997) |
| hypothetical mean strain | A hypothetical strain that possesses the characteristics of a calculated mean organism. (05 Mar 2000) |
| smooth strain | <microbiology> Bacterial strains that have altered outer cell wall carbohydrate chains causing colonies on agar to change their appearance from smooth to dull. In Streptococci the smooth strains are virulent whereas the rough strains are not. This is partly because the rough strains are much more readily phagocytosed. (17 Dec 1997) |
| neotype strain | A strain accepted by international agreement to replace a type strain which is no longer in existence or to serve as the type strain if a type strain was not designated and if no strain exists which can be designated as the type. Synonym: neotype culture. (05 Mar 2000) |
| stock strain | A bacterial or other microbial strain that has been maintained under laboratory conditions as representative of its type. (05 Mar 2000) |
| strain | A tearing injury to muscle. Usually causes some degree of bleeding within the muscle tissue (haematoma). (27 Sep 1997) |
| strain birefringence | <chemistry> Optical property of a material in which the refractive index is different for light polarized in one plane compared to the orthogonal plane. May arise from molecular organisation of the material (form birefringence.), alignment of molecules due to tension (stress birefringence.) or alignment of rod like particles in flow (flow birefringence). With crossed Nicoll prisms a birefringent material appears bright against a dark background. (19 Jan 1998) |