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type II interferon <chemical> The major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon (interferon type I) and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease.
Pharmacological action: antineoplastic agent, antiviral agents.
Chemical name: Interferon-gamma (human lymphocyte protein moiety reduced)
(12 Dec 1998)
type I interferon <chemical> Interferon secreted by leukocytes, fibroblasts, or lymphoblasts in response to viruses or interferon inducers other than mitogens, antigens, or allo-antigens. They include alpha- and beta-interferons (interferon-alpha and interferon-beta).
Pharmacological action: antineoplastic agent, antiviral agents.
(12 Dec 1998)
fibroblast interferon <cytokine> One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity.
Synonym: fibroblast interferon.
Pharmacological action: adjuvants, immunologic, antineoplastic agent, antiviral agents.
Chemical name: Interferon-alphaB (human leukocyte protein moiety reduced)
(12 Dec 1998)
leukocyte interferon <cytokine> One of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells when exposed to live or inactivated virus, double-stranded RNA, or bacterial products.
It is the major interferon produced by virus-induced leukocyte cultures and, in addition to its pronounced antiviral activity, causes activation of NK cells. It is used experimentally in the treatment of hairy-cell leukaemia.
A number of different subtypes exist that are elaborated by leukocytes in response to viral infection or stimulation with double-stranded RNA; IFN-alpha-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents.
See: interferon-alpha 2a, interferon-alpha 2b
Synonym: leukocyte interferon.
Pharmacological action: antineoplastic agent, antiviral agent.
(20 Sep 2002)
acetic solution A vinegar.
(05 Mar 2000)
amaranth solution A 1% solution of amaranth (trisodium naphthol sulfonic acid), a synthetic vivid red dye, stable in acid and intensified in sodium hydroxide solution; used as a red or pink colourant in liquid pharmaceuticals.
(05 Mar 2000)
aqueous solution <chemistry> A solution in which water is the dissolving medium or solvent.
(09 Jan 1998)
barium solution A liquid containing barium sulfate, which shows up on X-rays. It outlines organs of the body so they can be seen on X-ray film.
(12 Dec 1998)
Benedict's solution <chemistry> An aqueous solution of sodium citrate, sodium carbonate, and copper sulfate which changes from its normal blue colour to orange, red, or yellow in the presence of a reducing sugar such as glucose.
See: Benedict's test for glucose.
(14 Aug 2000)
Burow's solution A preparation of aluminium subacetate and glacial acetic acid, used for its antiseptic and astringent action on the skin.
(05 Mar 2000)
Gallego's differentiating solution A dilute solution of formaldehyde and acetic acid used in a modified Gram stain to differentiate and enhance the basic fuchsin binding to Gram-negative microorganisms.
(05 Mar 2000)
Gey's solution A salt solution usually used in combination with naturally occurring body substances (e.g., blood serum, tissue extracts) and/or more complex chemically defined nutritive solution's for culturing animal cells.
(05 Mar 2000)
glucose solution, hypertonic Solution that is usually 10 percent glucose but may be higher. An isotonic solution of glucose is 5 percent.
(12 Dec 1998)
volumetric solution A solution made by mixing measured volumes of the components.
(05 Mar 2000)
chemical solution See: solution.
(05 Mar 2000)
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