| gastric ulcer | <gastroenterology> An ulcer in the mucosal lining of the stomach. Ulcer formation results from gastric inflammation that may be triggered by the use of alcohol, aspirin or non-steroidal anti-inflammatories agents. Symptoms include recurrent abdominal pains (may be relieved by antacids), nausea, vomiting, weight loss and fatigue. Complications include GI bleeding, obstruction, perforation and ulcer penetration into surrounding tissues. Treatment includes the avoidance of alcohol, smoking, aspirin, anti-inflammatories and caffeine. Medications such as antacids or H2 antagonists (for example cimetidine, ranitidine) or proton pump inhibitors (omeprazole) have been shown to be effective treatment. (27 Sep 1997) |
|---|---|
| Mann-Williamson ulcer | <surgery> An operation performed on experimental animals (dogs) in research on peptic ulcer, the duodenum with its alkaline secretions being transplanted into the ileum and the cut end of the jejunum anastomosed to the pylorus. The animals develop ulcers in the jejunum which directly receives the gastric juice. (05 Mar 2000) |
| venereal ulcer | A sexually transmitted disease caused by the bacteria haemophilus ducreyi. Causes multiple painful ulcers on the penis and the vulva often associated with tender and enlarged inguinal lymph nodes. (27 Sep 1997) |
| marginal ring ulcer of cornea | A slowly advancing intermittent ulcer involving the circumference of the corneal margin. (05 Mar 2000) |
| genital ulcer disease | Ulcerative lesions on the genitals, usually caused by a sexually transmitted condition such as herpes, syphilis or chancroid. The presence of genital ulcers may increase the risk of transmitting HIV. (09 Oct 1997) |
| Marjolin's ulcer | Well-differentiated but aggressive squamous cell carcinoma occurring in cicatricial tissue at the epidermal edge of a sinus draining underlying osteomyelitis. (05 Mar 2000) |
| penetrating ulcer | An ulcer extending into deeper tissues of an organ. (05 Mar 2000) |
| Meleney's ulcer | Undermining ulcer of the skin and subcutaneous tissues, usually following an operation, caused by a synergistic interaction between microaerophilic nonhemolytic streptococci and aerobic haemolytic staphylococci. Synonym: Meleney's gangrene, progressive bacterial synergistic gangrene. (05 Mar 2000) |
| peptic ulcer | <gastroenterology> An ulcer in the wall of the stomach or duodenum resulting from the digestive action of the gastric juice on the mucous membrane when the latter is rendered susceptible to its action. (13 Nov 1997) |
| peptic ulcer perforation | Penetration of a peptic ulcer through the stomach wall. May be free, i.e., at a point where the stomach wall faces a real or potential space,, or confined, i.e., at a point where the stomach wall is defended by contiguous or adjacent structures, such as the pancreas. (12 Dec 1998) |
| perambulating ulcer | <dermatology> A rapidly spreading ulcer attended by the formation of extensive sloughing. Synonym: perambulating ulcer, sloughing ulcer, ulcus ambulans. Origin: L. Phagedaena, Gr Phago, To eat. (05 Mar 2000) |
| perforated ulcer | An ulcer extending through the wall of an organ. (05 Mar 2000) |
| perforating ulcer of foot | A round, deep, trophic ulcer of the sole of the foot, following disease or injury, in any part of its course from the centre to the periphery of the nerve supplying the part. Synonym: mal perforant. (05 Mar 2000) |
| chiclero ulcer | Lesion of the pinna of the ear due to cutaneous leishmaniasis, usually Leishmania mexicana; seen in workers harvesting chicle plants in Central America. Synonym: bay sore. Origin: Sp. Chicle farmer, fr. Chicle, fr. Nahuatl chictli (05 Mar 2000) |
| gravitational ulcer | A chronic ulcer of the leg with impaired healing because of the dependent position of the extremity and the incompetence of the valves of the varicosed veins; the venous return stagnates and creates hypoxaemia. See: varicose ulcer. (05 Mar 2000) |