| histamine headache | A term used to describe a headache that is typified by constant, unilateral pain around the eye, with onset usually within 2-3 hours of falling asleep. Can be accompanied by a blocked nasal passage, runny nose, and-or tearing. One may also notice facial flushing, ptosis (dropping eyelid), facial swelling and constriction of the pupils. (27 Sep 1997) |
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| histamine liberators | Substances that cause the release of histamine from mast cells or basophils. (05 Mar 2000) |
| histamine n-methyltransferase | <enzyme> An enzyme that catalyses the transfer of a methyl group from s-adenosylmethionine to histamine, forming n-methylhistamine, the major metabolite of histamine in man. Chemical name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase Registry number: EC 2.1.1.8 (12 Dec 1998) |
| histamine release | The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects. (12 Dec 1998) |
| histamine shock | The shock state produced in animals by the injection of histamine; characterised by bronchiolar spasm in the guinea pig and constriction of hepatic veins in the dog. (05 Mar 2000) |
| histamine test | A test for maximal production of gastric acidity or anacidity; after preliminary administration of an antihistamine, histamine acid phosphate is injected subcutaneously in a dose of 0.04 mg/kg of body weight, followed by analysis of gastric contents. Synonym: augmented histamine test. (05 Mar 2000) |
| acetyl phosphate | CH3CO-OPO32-;a "high energy" phosphate that acts as an acetate donor in the metabolism of various bacteria. Synonym: acetic phosphoric anhydride. (05 Mar 2000) |
| acidulated phosphate fluoride | <chemical> Phosphoric acid, mixt. With sodium fluoride (naf). A sodium fluoride solution, paste or powder, which has been acidulated to pH 3 to 4 and buffered with a phosphate. It is used in the prevention of dental caries. Pharmacological action: fluorides, topical. Chemical name: Phosphoric acid, mixt. With sodium fluoride (NaF) (12 Dec 1998) |
| acyl dihydroxyacetone phosphate oxidoreductase | <enzyme> Forms acyl-sn-glycerol 3-phosphate; uses NADPH Registry number: EC 1.1.1.- (26 Jun 1999) |
| adenosine 3',5'-cyclic phosphate phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine. Synonym: cAMP phosphodiesterase. (05 Mar 2000) |
| adenosine 3'-phosphate | 3'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine 3'-phosphate 5'-phosphosulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |
| adenosine 5'-phosphate | 5'-Adenylic acid. See: adenylic acid. (05 Mar 2000) |
| adenosine cyclic phosphate | An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known. Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate. Acronym: cAMP (05 Mar 2000) |
| alkyldihydroxyacetone phosphate acyltransferase | <enzyme> Catalyses acylation of alkyl-dhap Registry number: EC 2.3.1.- Synonym: adapat (26 Jun 1999) |