| heparin eliminase | <enzyme> An enzyme of the isomerase class that catalyses the eliminative cleavage of polysaccharides containing 1,4-linked d-glucuronate or l-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-d-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-d-gluc-4-enuronosyl groups at their non-reducing ends. Chemical name: heparin lyase Registry number: EC 4.2.2.7 (12 Dec 1998) |
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| heparin-glucosamine 3-O-sulfotransferase | <enzyme> Reaction: 3'-phosphoadenylylsulfate + heparin-glucosamine = adenosine 3',5'-bisphosphate + heparin glucosamine 3-o-sulfate Registry number: EC 2.8.2.23 Synonym: glucosaminyl 3-o-sulfotransferase, d-glucosaminyl 3-o-sulfotransferase (26 Jun 1999) |
| heparin, low-molecular-weight | <chemical> Heparin fractions with a molecular weight usually between 4000 and 6000 kD. These low-molecular-weight fractions are effective antithrombotic agents. Their administration reduces the risk of haemorrhage, they have a longer half-life, and their platelet interactions are reduced in comparison to unfractionated heparin. They also provide an effective prophylaxis against postoperative major pulmonary embolism. Pharmacological action: anticoagulant, fibrinolytic agent. (12 Dec 1998) |
| heparin lyase | <enzyme> An enzyme of the isomerase class that catalyses the eliminative cleavage of polysaccharides containing 1,4-linked d-glucuronate or l-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-d-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-d-gluc-4-enuronosyl groups at their non-reducing ends. Chemical name: heparin lyase Registry number: EC 4.2.2.7 (12 Dec 1998) |
| heparin unit | The quantity of heparin required to keep 1 ml of cat's blood fluid for 24 hr at 0°C; it is equivalent approximately to 0.002 mg of pure heparin. Synonym: Howell unit. (05 Mar 2000) |
| home infusion therapy | Use of any infusion therapy on an ambulatory, outpatient, or other non-institutionalised basis. (12 Dec 1998) |
| infusion | The therapeutic introduction of a fluid other than blood, as saline solution, solution, into a vein. (18 Nov 1997) |
| infusion-aspiration drainage | A type of drainage in which antibiotics are continuously infused into a cavity at the same time fluid is being drained (aspirated) from the cavity. Synonym: drip-suck irrigation. (05 Mar 2000) |
| infusion graft | Transplantation by injection of a suspension of cells. (05 Mar 2000) |
| infusion pumps | Fluid propulsion systems driven mechanically, electrically, or osmotically that are used to inject (or infuse) over time agents into a patient or experimental animal; used routinely in hospitals to maintain a patent intravenous line, to administer antineoplastic agent and other drugs in thromboembolism, heart disease, diabetes mellitus (insulin infusion systems is also available), and other disorders. (12 Dec 1998) |
| infusion pumps, implantable | Implanted fluid propulsion systems with self-contained power source for providing long-term controlled-rate delivery of drugs such as chemotherapeutic agents or analgesics. Delivery rate may be externally controlled or osmotically or peristaltically controlled with the aid of transcutaneous monitoring. (12 Dec 1998) |
| insulin infusion systems | Portable or implantable devices for infusion of insulin. Includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor. (12 Dec 1998) |
| intravenous infusion | <pharmacology> The giving of antibiotics, blood products, anti-cancer drugs or nutrients into a patients vein over a prolonged period of time. (30 Mar 1998) |