| HLA-dq antigens | <immunology> A group of the d-related HLA antigens found to differ from the dr antigens in genetic locus and therefore inheritance. These antigens are polymorphic glycoproteins comprising alpha and beta chains and are found on lymphoid and other cells, often associated with certain diseases. (12 Dec 1998) |
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| HLA-dr1 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. (12 Dec 1998) |
| HLA-dr2 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. It is in linkage disequilibrium with HLA-a3 and HLA-b7 and is strongly associated with goodpasture syndrome, multiple sclerosis, and narcolepsy. (12 Dec 1998) |
| HLA-dr3 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. It is in linkage disequilibrium with HLA-a1 and HLA-b8. The HLA-dr3 antigen is strongly associated with coeliac disease, grave's disease, dermatitis herpetiformis, early-age onset myasthenia gravis, systemic lupus erythematosus, juvenile diabetes, and opportunistic infections in aids. (12 Dec 1998) |
| HLA-dr4 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. It is strongly associated with rheumatoid arthritis and juvenile diabetes. (12 Dec 1998) |
| HLA-dr5 antigen | <immunology> Human immune-response, d-related antigen encoded by the d-locus on chromosome 6 and found on lymphoid cells. It is associated with kaposi sarcoma in aids and juvenile rheumatoid arthritis. (12 Dec 1998) |
| HLA-dr6 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. (12 Dec 1998) |
| HLA-dr7 antigen | <immunology> Human immune-response, d-related antigen encoded by the d locus on chromosome 6 and found on lymphoid cells. It is strongly associated with coeliac disease and psoriasis vulgaris. (12 Dec 1998) |
| HLA-dr antigens | <immunology> A group of d-related human leukocyte antigens that are polymorphic glycoproteins found on lymphoid cells. They consist of alpha and beta chains and their inheritance differs from that of the dq and dp antigens; their presence seems to be associated with certain skin diseases like pemphigus vulgaris, dermatitis herpetiformis, and type I diabetes. (12 Dec 1998) |
| HLA typing | <immunology> Tests done in order to determine if a patient has antibodies against a potential donor's HLA antigens. The presence of antibodies means that a particular graft will be rapidly rejected. (05 Mar 2000) |
| DNA probes, HLA | DNA probes specific for the human leukocyte antigen genes, which represent the major histocompatibility determinants in humans. The four known loci are designated as a, b, c, and d. Specific antigens are identified by a locus notation and number, e.g., HLA-a11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g., insulin-dependent diabetes mellitus). (12 Dec 1998) |