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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 2
  • Histamine H1 Antagonists - »õâ Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
    Synonyms : Antagonists, Histamine H1, Antagonists, Histamine H1 Receptor, Blockaders, Histamine H1 Receptor, H1 Receptor Blockaders, Histamine H1 Blockers, Receptor Blockaders, H1, Blockaders, H1 Receptor, Blockers, Histamine H1, Classical Antihistamines
  • Histamine H1 Antagonists, Non-Sedating - »õâ A class of non-sedating drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
    Synonyms : H1 Antihistamines, Non-Sedating, Second Generation Antihistamines, Second Generation H1 Antagonists, Antihistamines, Second Generation, H1 Antihistamines, Non Sedating, Histamine H1 Antagonists, Non Sedating, Non-Sedating H1 Antihistamines
  • Histamine H2 Antagonists - »õâ Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
    Synonyms : Antagonists, Histamine H2, Blockaders, Histamine H2 Receptor, H2 Receptor Blockaders, Histamine H2 Blockers, Receptor Antagonists, Histamine H2, Receptor Blockaders, H2, Blockaders, H2 Receptor, Blockers, Histamine H2, H2 Antagonists, Histamine
  • Histamine N-Methyltransferase - »õâ An enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to histamine, forming N-methylhistamine, the major metabolite of histamine in man. EC 2.1.1.8.
    Synonyms : Histamine N Methyltransferase, Methyltransferase, Histamine, N-Methyltransferase, Histamine
  • Histamine Release - »õâ The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's Fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects.
    Synonyms : Histamine Liberations, Histamine Releases
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 2
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