| 5 beta-cholestane-3 alpha,7 alpha-diol 26-hydroxylase |
<enzyme> Nadp-dependent
Registry number: EC 1.14.13.-
(26 Jun 1999) |
| 7 alpha-hydroxy-4-cholesten-3-one-12 alpha monooxygenase |
<enzyme> Liver microsomal enzyme active in conversion of cholesterol to cholic acid; introduces a 12 alpha-hydroxyl group into the steroid nucleus of cholesterol
Registry number: EC 1.14.99.-
Synonym: 7-hco-monooxygenase, hco 12 alpha-hydroxylase
(26 Jun 1999) |
| pregnancy-associated alpha-plasma protein |
An alpha 2-macroglobulin, molecular weight approximately 750,000 now believed to be a pregnancy-specific protein. Its plasma levels increase steadily during the second trimester and continue to rise until the end of gestation.
(12 Dec 1998) |
| I kappa B alpha-associated protein kinase |
<enzyme> Isolated from human monocytic cell line; phosphorylates ser(293), ser(288), and thr(291) of ikappabalpha
Registry number: EC 2.7.10.-
Synonym: ikappabalpha-associated protein kinase, ikappab-alpha-associated protein kinase, ikappabalpha kinase
(26 Jun 1999) |
| acetyl-CoA:alpha-glucosaminide acetyltransferase |
<enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C.
(05 Mar 2000) |
| adrenergic alpha-agonists |
Drugs that selectively bind to and activate alpha adrenergic receptors.
(12 Dec 1998) |
| adrenergic alpha-antagonists |
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
(12 Dec 1998) |
| alpha |
First letter of the Greek alphabet, a.
(05 Mar 2000) |
| alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase |
<enzyme> Incorporates n-acetyglucosamine as the third branch of complex n-glycosyl-oligosaccharide of hen oviduct
Registry number: EC 2.4.1.145
Synonym: glcnac-transferase iv, n-acetylglucosaminyltransferase iv, udp-glcnac-gngn(glcnac to man alpha1-3)beta 4-n-acetylglucosaminyltransferase iv
(26 Jun 1999) |
| alpha-1,4-glucan lyase |
<enzyme> Degrades alpha-1,4-glucan to produce 1,5-anhydrofructose; from seaweeds gracilariopsis lemaneiformis and gracilaria verrucosa; mw 111 kD; amino acid sequence has been determined
Registry number: EC 4.2.2.-
Synonym: alpha-1,4-glucan 4-lyase
(26 Jun 1999) |
| alpha 1-4-mannosyltransferase |
<enzyme> From mycobacterium smegmatis; involved in methylmannose polysaccharide elongation; GDP-mannose is donor
Registry number: EC 2.4.1.-
(26 Jun 1999) |
| alpha(1-6)mannosidase |
<enzyme> Human lysosomal enzyme highly specific for alpha 1-6 mannose residues; inhibited by swainsonine; not the same enzyme which is deficient in alpha-mannosidosis
Registry number: EC 3.2.1.-
(26 Jun 1999) |
| alpha 1,6-mannosyltransferase |
<enzyme> From saccharomyces cerevisiae; adds mannose residues in an alpha-1,6-linkage to man8glcnac and man9glcnac in the biosynthesis of the outer chain of yeast mannoproteins
Registry number: EC 2.4.1.-
(26 Jun 1999) |
| alpha-1 antichymotrypsin |
<chemical> Glycoprotein found in alpha(1)-globulin region in human serum. It is an inhibiter of the digestive protease, chymotrypsin and other chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro.
The protein also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumour marker. It is a member of the serpin superfamily.
Pharmacological action: serine proteinase inhibitors.
(12 Dec 1998) |
| alpha-1 antitrypsin |
<chemical> Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (a1pi), it exists in over 30 different biochemical variant forms known collectively as the pi (protease inhibitor) system.
Hereditary deficiency is associated with pulmonary emphysema.
See: alpha-1 antitrypsin deficiency
Pharmacological action: serine proteinase inhibitors, trypsin inhibitors.
(12 Dec 1998) |
