| factor H | Former designation for biotin, vitamin B12 analogue or precursor, a glycoprotein that regulates the activity of complement factor C3b; a deficiency results in the lack of inhibition of the alternative haemolytic pathway leading to continuous activation and consumption of factor C3 (haemolytic uraemic syndrome). (05 Mar 2000) |
|---|---|
| factor I | <haematology> A protein which is synthesised by the liver. Fibrinogen is converted to fibrin, in the formation of a blood clot, via the enzymatic action of thrombin. A fibrinogen assay measures the concentration of fibrinogen in the blood and may be used to evaluate abnormal blood clotting. A lack of fibrinogen may be congenital or acquired. A condition known as DIC results in the excessive utilisation and depletion of fibrinogen. Synonym: fibrinogen. (15 Nov 1997) |
| factor II | <haematology> A protein which is synthesised by the liver. Fibrinogen is converted to fibrin, in the formation of a blood clot, via the enzymatic action of thrombin. A fibrinogen assay measures the concentration of fibrinogen in the blood and may be used to evaluate abnormal blood clotting. A lack of fibrinogen may be congenital or acquired. A condition known as DIC results in the excessive utilisation and depletion of fibrinogen. Synonym: thrombin. (15 Nov 1997) |
| factor II assay | A test used to measure the activity of a blood clotting factor (thrombin). This test may be used to evaluate excessive bleeding. Abnormally low factor II assays may be seen in the following conditions: congenital deficiency of factor II, fat malabsorption, heparin administration, cirrhosis, vitamin K deficiency and warfarin administration. (27 Sep 1997) |
| factor II deficiency | A congenital or acquired disorder of blood clotting where there is a deficiency of factor II (prothrombin), one of 20 necessary plasma proteins for normal blood coagulation. Acquired factor II deficiency may result from vitamin K deficiency, severe liver disease and anticoagulant drugs. Symptoms include abnormal bleeding, nosebleeds, abnormal menstrual bleeding, easy bruising and umbilical cord bleeding at birth. Treatment involves the infusion of fresh frozen plasma. Vitamin K may be administered in select cases. (27 Sep 1997) |
| factor IIa | <enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. (18 Nov 1997) |
| factor III | In the clotting of blood, tissue factor or thromboplastin; it initiates the extrinsic pathway by reacting with factor VII and calcium to form factor VIIa. See: thromboplastin. (05 Mar 2000) |
| factor Inv | A factor that determines certain of the allotypes of human immunoglobulins; found on the kappa chains of IgG, IgA, IgM, and Bence Jones protein. (05 Mar 2000) |
| factor IV | In the clotting of blood, calcium ions. (05 Mar 2000) |
| factor ix | <chemical> Storage-stable blood coagulation factor acting in the intrinsic pathway. Its activated form, ixa, forms a complex with factor viii and calcium on platelet factor 3 to activate factor x to xa. Deficiency of factor ix results in christmas disease (haemophilia b). Chemical name: Blood-coagulation factor IX (12 Dec 1998) |
| factor ix assay | A test used to measure the activity of a blood clotting factor IX (Christmas factor). This test may be used to evaluate excessive bleeding. Abnormally low factor IX assays may be seen in the following conditions: congenital deficiency of factor IX, fat malabsorption, heparin administration, cirrhosis, vitamin K deficiency and warfarin administration. (27 Sep 1997) |
| factor ix deficiency | A form of haemophilia in males that results from a deficiency of clotting factor IX, transmitted as a X-linked trait. Symptoms include easy bruising, nosebleeds, bleeding gums and bleeding into muscle tissue (haematoma) or a joint space (haemarthrosis). Treatment includes the infusion of factor IX concentrates to normalize blood coagulation. (27 Sep 1997) |
| factor ixa | <enzyme> Activated form of factor ix. This activation can take place via the intrinsic pathway by the action of factor xia and calcium, or via the extrinsic pathway by the action of factor viia, thromboplastin, and calcium. Factor ixa serves to activate factor x to xa by cleaving the arginyl-leucine peptide bond in factor x. Registry number: EC 3.4.21.22 (12 Dec 1998) |
| factor P | A chemical (postulated by T. Lewis), formed in ischemic skeletal or cardiac muscle, held to be responsible for the pain of intermittent claudication and angina pectoris. (05 Mar 2000) |
| factor v | <chemical> Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor v accomplishes this by forming a complex with factor xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor v leads to owren's disease. Chemical name: Blood-coagulation factor V (12 Dec 1998) |
Synonyms : AC Globulin, Blood Coagulation Factor V, Factor Pi, Factor V, Coagulation, V, Coagulation Factor
Synonyms : Deficiency, Factor V, Owren's Disease, Deficiencies, Factor V, Disease, Owren, Disease, Owren's, Diseases, Owren, Diseases, Owren's, Factor V Deficiencies, Owren Diseases, Owren's Diseases, Owrens Disease, Parahemophilias
Synonyms : Blood Coagulation Factor V, Activated, Activated Factor V, Factor Va, Coagulation, Va, Coagulation Factor
Synonyms : Blood Coagulation Factor VII, Factor VII, Coagulation, Factor, Stable, VII, Coagulation Factor
Synonyms : Deficiency, Factor VII, Deficiencies, Factor VII, Factor VII Deficiencies, Hypoproconvertinemias
| factor V |
proaccelerin: a coagulation factor
출처: wordnet.princeton.edu/perl/webwn
|
|---|---|
| factor VII |
proconvertin: a coagulation factor formed in the kidney under the influence of vitamin K
출처: wordnet.princeton.edu/perl/webwn
|
| factor VIII |
antihemophilic factor: a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
출처: wordnet.princeton.edu/perl/webwn
|
| factor X |
prothrombinase: coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors
출처: wordnet.princeton.edu/perl/webwn
|
| factor XI |
plasma thromboplastin antecedent: coagulation factor whose deficiency results in a hemorrhagic tendency
출처: wordnet.princeton.edu/perl/webwn
|
| FACT | a segment of DNA found on a chromosome that codes for a particular protein |
|---|---|
| FACT | an abstract part of something |
| FACT | anything that contributes causally to a result |
| FACT | a businessman who buys or sells for another in exchange for a commission |
| FACT | any of the numbers (or symbols) that form a product when multiplied together |
| FACT | one of two or more integers that can be exactly divided into another integer |
| FACT | resolve into factors |
| FACT | a protein present in blood plasma |
| FACT | a protein in blood plasma that is the inactive precursor of thrombin |
| FACT | an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot |
| FACT | resolve into factors |
| FACT | ion of calcium |