| South American trypanosomiasis | Trypanosomiasis caused by Trypanosoma (or Schizotrypanum) cruzi and transmitted by certain species of reduviid (triatomine) bugs. In its acute form, it is seen most frequently in young children, with swelling of the skin at the site of entry, most often the face, and regional lymph node enlargement; in its chronic form it can assume several aspects, commonly cardiomyopathy, but megacolon and megaesophagus also occur; natural reservoirs include dogs, armadillos, rodents, and other domestic, domiciliated, and wild mammals. Synonym: Chagas' disease, Chagas-Cruz disease, Cruz trypanosomiasis. (05 Mar 2000) |
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| trypanosomiasis | <disease, microbiology> A parasitic disease caused by the American strain, Trypanosoma cruzi. Chagas disease is usually transmitted by the bite of the kissing bug, but may also follow breast feeding (to infants) and blood transfusion. Although much more common in South America, it does, on rare occasions, occur in the U.S. A nodular swelling (chagoma) appears at the site of inoculation following a bite. The acute phase of the disease can last 2 to 3 months and patients present with fever, headache, anorexia, conjunctivitis and myocarditis. Infants can develop meningitis and heart involvement. Trypanosomiasis can cause congestive heart failure and ventricular aneurysms. Treatment is with nifurtimox. (27 Sep 1997) |
| trypanosomiasis, bovine | Infection in cattle caused by various species of trypanosomes. (12 Dec 1998) |
| acute African sleeping sickness | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| african | Of or pertaining to Africa. African hemp, a fibre prerared from the leaves of the Sanseviera Guineensis, a plant found in Africa and India. African marigold, a tropical American plant (Tagetes erecta). African oak or African teak, a timber furnished by Oldfieldia Africana, used in ship building. Origin: L. Africus, Africanus, fr. Afer African. Source: Websters Dictionary (01 Mar 1998) |
| African endomyocardial fibrosis | Fibrosis of the inner layers of the myocardium, often including the endocardium, causing diastolic restriction of the heart; indigenous to East Africa. (05 Mar 2000) |
| African furuncular myiasis | Infection of man and animals with larvae of flies of the genus Cordylobia. Synonym: African furuncular myiasis, tumbu dermal myiasis. (05 Mar 2000) |
| african green monkey kidney cell | <cell culture> Cells taken from the kidneys of the African green monkey Cercopithecus aethiops sabaeus and used to grow certain viruses like poliovirus. (05 Feb 1998) |
| African haemorrhagic fever | Haemorrhagic fever associated with the morphologically similar but antigenically distinct Marburg and Ebola viruses. See: viral haemorrhagic fever. (05 Mar 2000) |
| african horse sickness | An insect-borne reovirus infection of horses, mules and donkeys in africa and the middle east; characterised by pulmonary oedema, cardiac involvement, and oedema of the head and neck. (12 Dec 1998) |
| african horse sickness virus | A species of orbivirus that causes disease in horses, mules, and donkeys. (12 Dec 1998) |
| african sleeping sickness | <infectious disease> A disease affecting humans and other mammals in central Africa that is caused by the parasitic protozoans Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense and is transmitted by the tsetse fly. Symptoms include fever, chills, headache, vomiting, pain in the extremities, lymph gland enlargement, anaemia, depression, fatigue, coma, and eventually death if left untreated. The trypanosome is able to evade the host's immune system by frequently changing the proteins on its outer surface, by which the immune system identifies intruders. (05 Feb 1998) |
| african swine fever | A usually fatal iridovirus infection of pigs, characterised by fever, cough, diarrhoea, haemorrhagic lymph nodes, and oedema of the gallbladder. (12 Dec 1998) |
| african swine fever-like viruses | An unnamed, unclassified genus of DNA viruses with a single species: african swine fever virus. (12 Dec 1998) |
| african swine fever virus | The lone species of the genus african swine fever-like viruses. The virus causes a fatal disease among domestic pigs in africa and a less virulent infection in europe. The virus is present in soft ticks (ornithodoros moubata), warthogs, or domestic pigs. Originally listed as a species of iridoviridae, the virus exhibits some similarities to poxviridae but its differences warranted placement in a separate genus of an, as yet unknown, family. (12 Dec 1998) |