| ERA | electrical response activity; electroencephalic response audiometry; Electroshock Research Associati... |
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| RR | radiation reaction; radiation response; rate ratio; rational recovery [group]; recovery room; relati... |
| RT | radiologic technologist; radiotelemetry; radiotherapy; radium therapy; rapid tranquilization; reacti... |
| ED | early-decision [applicant]; early differentiation; ectodermal dysplasia; ectopic depolarization; eff... |
| EMS | early morning specimen; early morning stiffness; electrical muscle stimulation; Electronic Medical S... |
| transcription factor ap-1 | A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerise in order to bind to the ap-1 recognition site, also known as the tpa-responsive element (tre). Ap-1 controls both basal and inducible transcription of several genes. (12 Dec 1998) |
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| transcription factor, sp1 | Promoter-specific RNA polymerase II transcription factor that binds to the gc box, one of the upstream promoter elements (upe) in mammalian cells. The binding of sp1 is necessary to initiate transcription in the promoters of a variety of cellular and viral genes including c-ha-ras and HIV. (12 Dec 1998) |
| transcription, genetic | The transfer of genetic information from DNA to messenger RNA by DNA-directed RNA polymerase. It includes reverse transcription and transcription of early and late genes expressed early in an organism's life cycle or during later development. (12 Dec 1998) |
| transcription unit | <molecular biology> A region of DNA that is transcribed to produce a single primary RNA transcript, i.e. A newly synthesised RNA molecule that has not been processed. Transcription units can be mapped by kinetic studies of RNA synthesis and in some instances directly visualised by electron microscopy. (17 Mar 1998) |
| erythroid transcription factor | <molecular biology> Transcription factor that binds to regulatory regions of genes expressed in erythroid cells. (18 Nov 1997) |
| adenovirus early proteins | <molecular biology, protein, virology> Proteins encoded by adenoviruses that are synthesised prior to, and in the absence of, viral DNA replication. The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation. (12 Dec 1998) |
| genes, immediate-early | Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters. (12 Dec 1998) |
| history of medicine, early modern | The period of the history of medicine from 1451 through 1600 a.d. History of medicine, 15th cent. And history of medicine, 16th cent. Are also available. (12 Dec 1998) |
| immediate early gene | Class of genes whose expression is low or undetectable in quiescent cells, but whose transcription is activated within minutes after extracellular stimulation such as addition of a growth factor. C fos and c myc proto-oncogenes were among the first IEG's to be identified. Many IEG's encode transcription factors and therefore have a regulatory function. (18 Nov 1997) |
| immediate-early proteins | Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesised just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesised immediately after the resting cell is stimulated by extracellular signals. (12 Dec 1998) |
| early | 1. In advance of the usual or appointed time; in good season; prior in time; among or near the first; opposed to late; as, the early bird; an early spring; early fruit. "Early and provident fear is the mother of safety." (Burke) "The doorsteps and threshold with the early grass springing up about them." (Hawthorne) 2. Coming in the first part of a period of time, or among the first of successive acts, events, etc. "Seen in life's early morning sky." (Keble) "The forms of its earlier manhood." (Longfellow) "The earliest poem he composed was in his seventeenth summer." (J. C. <philosophy> Shairp) Early English See the Note under English. Early English architecture, the first of the pointed or Gothic styles used in England, succeeding the Norman style in the 12th and 13th centuries. Synonym: Forward, timely, not late, seasonable. Origin: OE. Earlich. See Early. Source: Websters Dictionary (01 Mar 1998) |
| early ambulation | Procedure characterised by a shorter period of hospitalization or recumbency or by more rapid mobilization than is normally practiced. (12 Dec 1998) |
| early deceleration | Slowing of the foetal heart rate early in the uterine contraction phase, denoting compression of the foetal head. (05 Mar 2000) |
| early development | An early stage in the life cycle of a bacteriophage (a virus which infects bacteria) that occurs after infection but before replication of the bacteriophage genome. (09 Oct 1997) |
| early diastolic murmur | A murmur that begins with the second heart sound, as the murmur of aortic insufficiency. (05 Mar 2000) |