| eosinophil cationic protein | <protein> Arginine rich protein (21 kD) in granules of eosinophils, that damages schistosomula in vitro. Not the same as the MBP (major basic protein) of the granules. (18 Nov 1997) |
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| eosinophil chemotactic factor of anaphylaxis | A peptide (MW 500 to 600) that is chemotactic for eosinophilic leukocytes and is released from disrupted mast cells. (05 Mar 2000) |
| eosinophil chemotactic peptide | <protein> Tetrapeptides (of which two are identified: VGSE and AGSE) released by mast cells and that are said to both attract and activate eosinophils. (18 Nov 1997) |
| eosinophil count | A measurement (cells per microlitre) of the number of eosinophils in a blood specimen. This measurement, also called the absolute eosinophil count, is useful in the evaluation of autoimmune disease, allergies, eczema, leukaemia, asthma and hay fever. Normal absolute eosinophil counts are less than 350 cells/mcl (microlitre). (27 Sep 1997) |
| eosinophil granule | A granule that stains with eosin. (05 Mar 2000) |
| eosinophil peroxidase | <enzyme> Peroxidase from eosinophil granules distinct from myeloperoxidase; claimed to enhance destruction of fungi, bacteria, schistosomula, toxoplasma, trypanosoma, mast cells, tumour cells in presence of exogenous h2o2 and halide Registry number: EC 1.11.1.- (26 Jun 1999) |
| eosinophilia | <haematology> The formation and accumulation of an abnormally large number of eosinophils in the blood. Origin: Gr. Philein = to love (18 Nov 1997) |
| eosinophilia-myalgia syndrome | <syndrome> A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. The varied symptoms include severe muscle pain and abnormally high numbers of eosinophils. This disease has presented itself only in people taking the amino acid l-tryptophan and it is believed that a specific impurity (probably stemming from a genetically engineered bacterial strain) in lots of l-tryptophan made by a single manufacturer may be the cause of the syndrome. (12 Dec 1998) |
| eosinophilic | Staining readily with eosin dyes; denoting such cell or tissue elements. (05 Mar 2000) |
| eosinophilic cellulitis | <syndrome> Recurrent cellulitis followed by brawny edematous skin lesions, or a less acute presentation of papular, annular, or gyrate skin lesions which are sometimes urticarial; affected skin and subcutis are heavily infiltrated by eosinophils and histiocytes, with scattered small necrotic foci (flame figures) of varied aetiology; sometimes follows an arthropod bite. Synonym: eosinophilic cellulitis. (05 Mar 2000) |
| eosinophilic cystitis | Bladder inflammation with many eosinophils in urinary sediment as well as bladder wall. (05 Mar 2000) |
| eosinophilic endomyocardial disease | A restrictive cardiomyopathy associated with hyperproduction of eosinophiles and their cardiac infiltration, clinically characterised by diastolic and later systolic ventricular failure. (05 Mar 2000) |
| eosinophilic fasciitis | <pathology> A syndrome which is characterised by inflammation of the fascia and muscles of the extremities. Infiltrations of eosinophils are found in affected muscle tissue and fascia. The cause is unknown. Symptoms include tenderness and swelling of arms and legs, joint contractures, bone apins, muscle aches and muscle weakness. Some may complain of carpal tunnel syndrome symptoms with numbness and tingling in the hands. Diagnosis is made by tissue biopsy. Treatment includes systemic corticosteroids. The illness can last for 3 to 5 years and then ususally resolves. (27 Sep 1997) |
| eosinophilic gastritis | <radiology> Eosinophilic infiltration of mucosa, submucosa, and muscularis of small bowel with or without stomach, stomach (almost always limited to antrum): enlarged gastric rugae, cobblestone nodules, polyps (=mucosal type), rigid wall with narrowed antrum/pylorus, bulky inramural mass up to 9 cm (=muscular type), wet stomach, ulcers rare, may have ascites, small bowel (predominantly jejunum), thickening and distortion of folds (=mucosal type), effacement of mucosa and narrowing of lumen (=muscular type), prognosis: tendency to spontaneous remission, treatment: steroids; removal of sensitizing agent (12 Dec 1998) |
| eosinophilic gastroenteritis | <radiology> Eosinophilic infiltration of mucosa, submucosa, and muscularis of small bowel with or without stomach, stomach (almost always limited to antrum): enlarged gastric rugae, cobblestone nodules, polyps (=mucosal type), rigid wall with narrowed antrum/pylorus, bulky inramural mass up to 9 cm (=muscular type), wet stomach, ulcers rare, may have ascites, small bowel (predominantly jejunum), thickening and distortion of folds (=mucosal type), effacement of mucosa and narrowing of lumen (=muscular type), prognosis: tendency to spontaneous remission, treatment: steroids; removal of sensitizing agent (12 Dec 1998) |