| diphtheria toxin | <protein> An ab exotoxin (62 kD) coded by _ corynephage of virulent Corynebacterium diphtheriae strains (that can produce a repressor of toxin production). The B subunit binds to receptors on the surface of the target cell and facilitates the entry of the enzymically active A subunit (21 kD) that ADP ribosylates elongation factor 2, thereby halting mRNA translation. (18 Nov 1997) |
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| diphtheria toxoid | The formaldehyde-inactivated toxin of corynebacterium diphtheriae. It is generally used in mixtures with tetanus toxoid and pertussis vaccine (dtp) or with tetanus toxoid alone (dt for paediatric use and td, which contains 5- to 10-fold less diphtheria toxoid, for other use). Diphtheria toxoid is used for the prevention of diphtheria; diphtheria antitoxin is for treatment. (12 Dec 1998) |
| false diphtheria | 1. One of a group of local infections suggesting diphtheria, but caused by microorganisms other than Corynebacterium diphtheriae. Synonym: Epstein's disease, false diphtheria, pseudodiphtheria. 2. Any microorganism resembling Corynebacterium diphtheriae. Origin: diphtheria + G. Eidos, resemblance (05 Mar 2000) |
| faucial diphtheria | Severe pharyngitis affecting the fauces, the usual site affected by infection with Corynebacterium diphtheriae. (05 Mar 2000) |
| laryngeal diphtheria | Diphtheria affecting the larynx, usually with asphyxiation due to obstruction of the airway by the membrane that forms, with fatal outcome. Synonym: laryngotracheal diphtheria. (05 Mar 2000) |
| laryngotracheal diphtheria | Diphtheria affecting the larynx, usually with asphyxiation due to obstruction of the airway by the membrane that forms, with fatal outcome. Synonym: laryngotracheal diphtheria. (05 Mar 2000) |
| fowl diphtheria | An infection by the fowlpox virus in which tracheal involvement is especially severe. See: fowlpox. Synonym: fowl diphtheria. (05 Mar 2000) |