| TOP | termination of pregnancy; topoisomerase |
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| top | topical |
| TEF | Tracheo-Esophageal Fistula ? Tx 1. Infant Warmer ... |
| BD | barbital-dependent; barbiturate dependence; base deficit; base of prism down; basophilic degeneratio... |
| CAGE | cut down, annoyed by criticism, guilty about drinking, eye-opener drinks (a test for alcoholism) |
| down-regulation | <physiology> Development of a refractory or tolerant state consequent upon repeated administration of a pharmacologically or physiologically active substance. It is the process that decreases ligand and receptor interactions or reduces the responsiveness of a cell to a stimulus following first exposure. This is often accompanied by an initial decrease in affinity of receptors for the agent and a subsequent reduction in the number of available receptors expressed on the surface which can result from internalisation of the ligand:receptor complex or from decreased expression of the receptor. Classically the concept referred to hormone receptors but contemporary usage includes other cell surface receptors. (03 Jul 1999) |
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| Down's syndrome | <genetics, syndrome> A congenital disorder in which a person is born with three copies of chromosome 21 (trisomy 21). Clinical features include moderate to severe mental retardation, slanting eyes, a broad short skull, broad hands and short fingers. Other congenital abnormalities include heart defects, oesophageal atresia and an increased incidence of acute lymphocytic leukaemia. Trisomy 21 can be detected in the first few months of pregnancy by amniocentesis. Risk factors include prior child with Down's syndrome and mothers who become pregnant after age 40. This disorder was formerly known as mongolism. Incidence: 1 in 1000 births. (09 Oct 1997) |
| down syndrome | <radiology> Trisomy 21, mongolism, atlantoaxial subluxation, Wormian bones, absent/small paranasal sinuses, endocardial cushion (AV canal) defects, aberrant right subclavian artery, 2 ossification centres for manubrium (90%), 11 or 13 ribs, duodenal atresia / stenosis, tracheo-oesophageal fistula, Hirschsprung disease (12 Dec 1998) |
| turn down ratio | The lowest load at which a boiler will operate efficiently as compared to the boiler's maximum design load. (05 Dec 1998) |
| let-down reflex | <neurology, paediatrics> An involuntary reflex during breast feeding which causes the milk to flow freely. See: milk-ejection reflex (22 Sep 2002) |
| anterior deep cervical lymph nodes | The lymph nodes near the larynx, trachea, and thyroid gland. Synonym: nodi lymphatici cervicales anteriores profundi. (05 Mar 2000) |
| rapture of the deep | See: nitrogen narcosis. (05 Mar 2000) |
| preauricular deep parotid lymph nodes | Small lymph nodes located deep to the parotid fascia and in front of the ear. Synonym: preauricular deep parotid lymph nodes. (05 Mar 2000) |
| skin-deep | Not deeper than the skin; hence, superficial. Source: Websters Dictionary (01 Mar 1998) |
| small deep petrosal nerve | <anatomy, nerve> One of two sympathetic branches from the internal carotid plexus to the tympanic plexus. Synonym: nervus caroticotympanicus, small deep petrosal nerve. (05 Mar 2000) |
| superficial layer of deep cervical fascia | The part of the cervical fascia investing the sternocleidomastoid and trapezius muscles and completely encircling the neck. Synonym: lamina superficialis fasciae cervicalis, investing fascia, superficial layer of deep cervical fascia. (05 Mar 2000) |
| deep | 1. Extending far below the surface; of great perpendicular dimension (measured from the surface downward, and distinguished from high, which is measured upward); far to the bottom; having a certain depth; as, a deep sea. "The water where the brook is deep." (Shak) 2. Extending far back from the front or outer part; of great horizontal dimension (measured backward from the front or nearer part, mouth, etc); as, a deep cave or recess or wound; a gallery ten seats deep; a company of soldiers six files deep. "Shadowing squadrons deep." (Milton) "Safely in harbor Is the king's ship in the deep nook." (Shak) 3. Low in situation; lying far below the general surface; as, a deep valley. 4. Hard to penetrate or comprehend; profound; opposed to shallow or superficial; intricate; mysterious; not obvious; obscure; as, a deep subject or plot. "Speculations high or deep." (Milton) "A question deep almost as the mystery of life." (De Quincey) "O Lord, . . . Thy thought are very deep." (Ps. Xcii. 5) 5. Of penetrating or far-reaching intellect; not superficial; thoroughly skilled; sagacious; cunning. "Deep clerks she dumbs." (Shak) 6. Profound; thorough; complete; unmixed; intense; heavy; heartfelt; as, deep distress; deep melancholy; deep horror. "Deep despair." . "Deep silence." . "Deep sleep." . "Deeper darkness." . "Their deep poverty." . "An attitude of deep respect." (Motley) 7. Strongly coloured; dark; intense; not light or thin; as, deep blue or crimson. 8. Of low tone; full-toned; not high or sharp; grave; heavy. "The deep thunder." "The bass of heaven's deep organ." (Milton) 9. Muddy; boggy; sandy; said of roads. "The ways in that vale were very deep." (Clarendon) A deep line of operations, mourning complete and strongly marked, the garments being not only all black, but also composed of lusterless materials and of such fashion as is identified with mourning garments. Origin: OE. Dep, deop, AS. Deop; akin to D. Diep, G. Tief, Icel. Djpr, Sw. Diup, Dan. Dyb, Goth. Diups; fr. The root of E. Dip, dive. See Dip, Dive. Source: Websters Dictionary (01 Mar 1998) |
| deep abdominal reflexes | Contraction of abdominal muscles elicited by stimulation, such as tapping a deep structure; e.g., the costal margin. See: Galant's reflex, upper abdominal periosteal reflex. (05 Mar 2000) |
| deep artery of clitoris | The deep terminal branch of the internal pudendal artery in the female; it supplies the crus of the clitoris. Synonym: arteria profunda clitoridis. (05 Mar 2000) |
| deep artery of penis | Origin, terminal branch (with dorsal artery of penis) of the internal pudendal artery; distribution, corpus cavernosum of the penis via capillary beds and via helcine arteries and arteriovenous anastomoses to produce erection. Synonym: arteria profunda penis. (05 Mar 2000) |