| GAP syndrome | Galactorrhea, Amenorrhea, Prolactinoma Syndrome |
|---|---|
| OG | Osmolar Gap; 10 mOsm/kg = measured Osm - calculated Osm |
| AG | abdominal girth; agarose; aminoglutethimide; analytical grade; anion gap; antigen; antiglobulin; ant... |
| csg | chromosome gap |
| ctg | chromated gap |
| gap junctions | Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junctions. (12 Dec 1998) |
|---|---|
| gap mutant | <molecular biology> A fruit fly of the genus Drosophila which is missing a number of adjacent segments because the segments failed to develop. (09 Oct 1997) |
| gap phenomenon | A short period in the cycle of the atrioventricular or intraventricular conduction allowing passage of an impulse which at other times would be blocked in transit. Synonym: excitable gap. (05 Mar 2000) |
| GAP protein | <molecular biology> Originally purified as a 125 kD protein from bovine brain (1044 amino acids), stimulates the GTPase activity of ras p21 and thereby switches it to the inactive state. GAP may itself be regulated by phospholipids and by phosphorylation on a tyrosine residue by growth factor receptors (PDGF R, EGF R). The neurofibromatosis type 1 gene NF1) codes for a protein homologous to GAP. GAP has both SH2 and SH3 domains. Another example is sar 1 (from yeast). (18 Nov 1997) |
| chromosomal gap | A localised area of thinning in a chromatid which may simulate a complete break. (05 Mar 2000) |
| silent gap | The period during which Korotkoff sounds indicating true systolic pressure fade away and reappear at a lower pressure point; responsible for errors made in recording falsely low systolic blood pressure, especially in hypertensive patients, of up to 25 mm Hg, and avoided by pumping the cuff 30 mm Hg beyond palpable systolic pressure. Synonym: silent gap. (05 Mar 2000) |
| interocclusal gap | The space between the occluding surfaces of the maxillary and mandibular teeth when the mandible is in physiologic resting position. Synonym: interocclusal clearance, interocclusal distance, interocclusal gap, interocclusal rest space. (05 Mar 2000) |
| excitable gap | A short period in the cycle of the atrioventricular or intraventricular conduction allowing passage of an impulse which at other times would be blocked in transit. Synonym: excitable gap. (05 Mar 2000) |
| A-DNA | A form of DNA in which the helix is right-handed and the overall appearance is short and broad. (05 Mar 2000) |
| a-form DNA | <molecular biology> One of several forms that can be assumed by a double helix. A-DNA is stable in dehydrated conditions. This form is less common than the dominant form found under physiological conditions -- beta-DNA. This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA. (09 Oct 1997) |
| antisense DNA | <molecular biology> A synthetic DNA strand that is complementary to a particular strand of target DNA with a complementary sequence of bases. This results in preventing expression of the gene encoded. These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. (14 Nov 1997) |
| apurinic DNA | <molecular biology> A DNA molecule that has lost adenine and guanine, its purine bases. Apurinic DNA can be produced by treating the DNA with acid. (09 Oct 1997) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| bacteriophage T7 induced DNA polymerase | <enzyme> Complex of two proteins, phage gene 5 protein and E coli thioredoxin Registry number: EC 2.7.7.- Synonym: t7 phage DNA polymerase, sequenase, t7 DNA polymerase, thermo sequenase (26 Jun 1999) |
| base in DNA | A unit of the DNA. There are 4 bases: adenine (A), guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is the genetic code. (12 Dec 1998) |