| dideoxy sequencing | The most popular method of DNA sequence determination (c.f. Maxam Gilbert sequencing). Starting with single stranded template DNA, a short complementary primer is annealed and extended by a DNA polymerase. The reaction is split into 4 tubes (called A, C, G or T) each containing a low concentration of the indicated dideoxy nucleotide, in addition to the normal deoxynucleotides. Dideoxynucleotides, once incorporated, block further chain extension and so each tube accumulates a mixture of chains of lengths determined by the template sequence. The 4 reactions are denatured and run out on an acrylamide sequencing gel in neighbouring lanes and the sequence read up the gel according to the order of the bands. (18 Nov 1997) |
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| dideoxyadenosine | <chemical> A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolised to didanosine (ddi) by enzymatic deamination; ddi is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite. Pharmacological action: antimetabolites, antiviral agents. Chemical name: Adenosine, 2',3'-dideoxy- (12 Dec 1998) |
| dideoxycytidine | Pyrimidine nucleoside analog with antiviral activity; has been tried in AIDS. (05 Mar 2000) |
| dideoxyinosine | Antiviral agent; has been used in treatment of AIDS. Acronym: DDI (05 Mar 2000) |
| dideoxynucleosides | <chemical> Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription. Pharmacological action: antimetabolites, antiviral agents, reverse transcriptase inhibitors. (12 Dec 1998) |
| dideoxynucleotide | <biochemistry> A deoxynucleotide that lacks a 3' hydroxyl group, and is thus unable to form a 3'-5' phosphodiester bond necessary for chain elongation. Dideoxynucleotides are used in DNA sequencing and the treatment of viral diseases. (09 Oct 1997) |
| didine | <zoology> Like or pertaining to the genus Didus, or the dodo. Source: Websters Dictionary (01 Mar 1998) |
| didonia | <geometry> The curve which on a given surface and with a given perimeter contains the greatest area. Origin: NL. So called in allusion to the classical story of Dido and the bull's hide. Source: Websters Dictionary (01 Mar 1998) |
| dids | <chemical> 2,2'-(1,2-ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid). An inhibitor of anion conductance including band 3-mediated anion transport. Chemical name: Benzenesulfonic acid, 2,2'-(1,2-ethenediyl)bis(5-isothiocyanato- (12 Dec 1998) |
| didym- | <prefix> relating to the didymus or testis. Origin: G. Didymos, twin (21 Jun 2000) |
| didymium | <chemistry> A rare metallic substance usually associated with the metal cerium; hence its name. It was formerly supposed to be an element, but has since been found to consist of two simpler elementary substances, neodymium and praseodymium. Origin: NL, fr. Gr. Twin. Source: Websters Dictionary (01 Mar 1998) |
| didymous | <plant biology> Carried in pairs, of anthers, having two lobes, with scarcely any tissue connecting them. (09 Oct 1997) |
| didymus | 1. An alternive term for the testis. Origin: G. Didymos, a twin, pl. Didymoi, testes 2. <suffix> A conjoined twin, with the first element of the complete word designating fused parts. See: -dymus, -pagus. Origin: G. Didymos, twin (21 Jun 2000) |
| didynamia | <botany> A Linnaean class of plants having four stamens disposed in pairs of unequal length. Origin: NL, fr. Gr. = twice + power. Source: Websters Dictionary (01 Mar 1998) |
| didynamous | Of stamens: four in number, two being distinctly longer than the other two. (09 Oct 1997) |
| didanosine |
A nucleoside reverse transcriptase inhibitor first approved by the FDA in 1991 and used for the treatment of HIV infection when antiretroviral therapy is warranted. Also called ddl, Videx.
출처: www.thebody.com/hivatis/glossary/d.html
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| didymous |
borne in pairs; of anthers, having two lobes, with scarcely any tissue connecting them.
출처: www.deh.gov.au/biodiversity/abrs/online-resources/...
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| didactylous |
Having unfused digits of the hand or feet (eg two-toed sloth)
출처: www.uoguelph.ca/~mammals/Mammalogy_2005_glossary.h...
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| didactic |
offered with the intention of instruction or teaching.
출처: www.filosofia.net/materiales/rec/glosaen.htm
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| didactic |
providing instruction. Didactic literature may be quite pointedly or narrowly instructive, intended to instill specific moral or cultural values. But the term can also be applied more generally to focus on the intentionality of the literary text and on reading/writing as a purposive activity.
출처: www2.cumberlandcollege.edu/acad/english/litcritweb...
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| DID | opossums |
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| DID | type genus of the family Didelphidae |
| DID | omnivorous opossum of the eastern United States |
| DID | omnivorous opossum of the eastern United States |
| DID | French philosopher who was a leading figure of the Enlightenment in France |
| DID | United States writer (born in 1834) |
| DID | (Roman mythology) a princess of Tyre who was the founder and queen of Carthage |
| DID | outstanding United States athlete (1914-1956) |