| diabetes insipidus | <disease, endocrinology> Rare form of diabetes in which the kidney tubules do not reabsorb sufficient water. This can be because (a) either the renal tubules have defective receptors for antidiuretic hormone (ADH, vasopressin) or (b) a class of aquaporin water channel in the collecting duct is defective or (c) there is inadequate ADH production by the pituitary, leading to the excessive production of dilute urine. (18 Nov 1997) |
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| diabetes insipidus, nephrogenic | A rare congenital and familial form of diabetes insipidus, resulting from failure of the renal tubules to absorb water. There is excessive production of antidiuretic hormones but the tubules fail to respond to it. (12 Dec 1998) |
| diabetes intermittens | Diabetes mellitus in which there are periods of relatively normal carbohydrate metabolism followed by relapses to the previous diabetic state. (05 Mar 2000) |
| diabetes mellitus | <disease> Relative or absolute lack of insulin leading to uncontrolled carbohydrate metabolism. In juvenile onset diabetes (that may be an autoimmune response to pancreatic _ cells) the insulin deficiency tends to be almost total, whereas in adult onset diabetes there seems to be no immunological component but an association with obesity. (18 Nov 1997) |
| diabetes mellitus, experimental | Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by pancreatectomy. (12 Dec 1998) |
| diabetes mellitus, insulin-dependent | Diabetes mellitus characterised by insulin deficiency, sudden onset, severe hyperglycaemia, rapid progression to ketoacidosis, and death unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence. (12 Dec 1998) |
| diabetes mellitus, lipoatrophic | A disorder characterised by complete absence of subcutaneous adipose tissue, insulin-resistant diabetes with little tendency to ketoacidosis, hyperlipidemia with subcutaneous xanthomatosis, hepatomegaly, and an elevated basal metabolic rate. (12 Dec 1998) |
| diabetes mellitus, non-insulin-dependent | Diabetes characterised by the ability to survive without ketoacidosis in the absence of insulin therapy. It is usually of slow onset and patients exhibit a tendency to obesity. (12 Dec 1998) |
| diabetes related peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
| diabetes, gestational | A diabetic condition that appears during pregnancy (gestation) and may go away after the birth of the baby. (12 Dec 1998) |
| diabetes, type 1 | Insulin dependent diabetes or juvenile diabetes. (12 Dec 1998) |
| diabetes, type 2 | Non-insulin dependent diabetes, adult-onset diabetes or insulin-resistant diabetes. (12 Dec 1998) |
| diabetic | Diabetes mellitus is a disorder that is caused by the insufficient production of the pancreatic hormone insulin. Without insulin cells are unable to absorb glucose, necessary for cellular metabolism and energy production. Patients may have type I diabetes (juvenile onset) or type II diabetes (adult onset). Individuals with either condition are considered to be diabetic. (27 Sep 1997) |
| diabetic acidosis | Decreased pH and bicarbonate concentration in the body fluids caused by accumulation of ketone bodies in diabetes mellitus. (05 Mar 2000) |
| diabetic amyotrophy | A type of diabetic neuropathy that primarily affects elderly patients with diabetes mellitus; clinically characterised by unilateral or bilateral anterior thigh pain, weakness, and atrophy; of abrupt or gradual onset and, when bilateral, of simultaneous or sequential onset, and usually asymmetrical; one type of diabetic polyradiculopathy. Sometimes referred to, erroneously, as diabetic femoral neuropathy. (05 Mar 2000) |