| inclusion body disease | <disease> An illness in newborns caused by viral infection, symptoms includefever, cellular enlargement, microscopically-visible clumps of viralparticles or proteins in the cytoplasm and nuclei of affected cells, enlargementof the spleen and liver. Long-term effects of the disease may includemental retardation. (09 Oct 1997) |
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| inclusion body encephalitis | <neurology> Chronic progressive illness seen in children a few years after measles infection and involving demyelination of the cerebral cortex. Virus apparently persists in brain cells: usually considered a slow virus disease. (18 Nov 1997) |
| inclusion body myositis | <radiology> Common form of inflamatory myopathy, most common in the elderly, equal sex incidence, sporadic idiopathic disease (very rarely familial), misdiagnosed as steroid-resistant polymyositis symptoms, presents as a painless slowly progressive proximal myopathy, may cause dysphagia, mild to moderate muscle wasting diagnosis, serum creatine kinase levels usually normal or only slightly elevated, EMG may show non-specific myopathic features, diagnosis on muscle biopsy, inclusion bodies seen in rimmed vacuoles in skeletal muscle fibres treatment, steroids and immunosuppression generally ineffective, rare patients reported who have made a response to treatment pathogenesis, unknown, ubiquitin, prion protein, tau protein found in inclusions, abnormal mitchondria seen in some case (12 Dec 1998) |
| inclusion body rhinitis | A respiratory disease of pigs caused by the cytomegalovirus porcine herpesvirus 2 and characterised by rhinitis and conjunctivitis in young pigs. (05 Mar 2000) |
| inclusion cell | i cell |
| inclusion cell disease | <biochemistry> Mucolipidosis of early onset and with severe symptoms like those in Hurler's syndrome but with normal urinary mucopolysaccharides, vacuolated lymphocytes, and inclusion bodies in cultured fibroblasts (I-cells). The lysosomes lack hydrolases but high concentrations of lysosomal enzymes are found in the extracellular fluids such as serum, spinal fluid, and urine. It is associated with a deficiency of N-acetylglucosaminyl-1-phosphotransferase. The gene defect responsible probably prevents the addition of the lysosome recognition marker mannose 6 phosphate) to these enzymes so that they are not directed into the lysosomes but are released. Inheritance: autosomal recessive. Synonym: I-cell disease, inclusion cell disease. (12 Jul 2000) |
| inclusion compound | The mechanical trapping of small molecules within spaces between other molecules; e.g., the inclusion of iodine molecules by starch molecules to form the well-known red-to-black "addition compound" (05 Mar 2000) |
| inclusion conjunctivitis | A follicular conjunctivitis caused by Chlamydia trachomatis. (05 Mar 2000) |
| inclusion conjunctivitis viruses | Former name for Chlamydia trachomatis. (05 Mar 2000) |
| inclusion cyst | Intradermal or subcutaneous saclike structure, the wall of which is stratified epithelium containing keratohyalin granules. (12 Dec 1998) |
| inclusion dermoid | A collection of cancerous cells which form cysts that contain one or more of the three primary embryonic germ layers: skin, hair or teeth. (27 Sep 1997) |
| epidermoid inclusion cyst | <radiology> Well-circumscribed radiolucent lesion showing a thin cortical margin that may not be visible in its entirety, frequently in the terminal phalanx, history of penetrating trauma is often elicited Differential diagnosis: ABC, enchondroma (12 Dec 1998) |
| foetal inclusion | Unequal conjoined twins in which the incompletely developed parasite is wholly enclosed in the autosite. (05 Mar 2000) |
| alcoholic hyaline bodies | Large, poorly defined accumulations of eosinophilic material in the cytoplasm of damaged hepatic cells in certain forms of cirrhosis and marked fatty change especially due to alcoholism. Synonym: alcoholic hyalin, alcoholic hyaline bodies. (05 Mar 2000) |
| Alder bodies | Granular inclusions in polymorphonuclear leukocytes; they take on a dark colour with Giemsa-Wright stain and react metachromatically with toluidine blue. See: Alder's anomaly. (05 Mar 2000) |