| DCT | direct Coombs' test; discrete cosine transform; distal convoluted tubule; diurnal cortisol test; dyn... |
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| ICT | icteric, icterus; indirect Coombs test; inflammation of connective tissue; insulin coma therapy; int... |
| direct Coombs' test | A test for detecting sensitised erythrocytes in erythroblastosis foetalis and in cases of acquired immune haemolytic anaemia: the patient's erythrocytes are washed with saline to remove serum and unattached antibody protein, then incubated with Coombs' anti-human globulin (usually serum from a rabbit or goat previously immunised with human globulin); after incubation, the system is centrifuged and examined for agglutination, which indicates the presence of so-called incomplete or univalent antibodies on the surface of the erythrocytes. (05 Mar 2000) |
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| indirect Coombs' test | A test routinely performed in cross-matching blood or in the investigation of transfusion reaction: test for patient's serum is incubated with a suspension of donor erythrocytes; if specific antibodies are present, they become attached to the antigen in donor's cells; after a washing with saline, Coombs' antihuman globulin is added; agglutination at this point indicates that antibodies present in the original test serum had indeed become attached to donor erythrocytes. (05 Mar 2000) |