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somatotropin release-inhibiting factor <protein> Gastrointestinal and hypothalmic peptide hormone (two forms: 14 and 28 residues), found in gastric mucosa, pancreatic islets, nerves of the gastrointestinal tract, in posterior pituitary and in the central nervous system. Inhibits gastric secretion and motility: in hypothalamus/pituitary inhibits somatotropin release.
(18 Nov 1997)
somatotropin release-inhibiting hormone <protein> Gastrointestinal and hypothalmic peptide hormone (two forms: 14 and 28 residues), found in gastric mucosa, pancreatic islets, nerves of the gastrointestinal tract, in posterior pituitary and in the central nervous system. Inhibits gastric secretion and motility: in hypothalamus/pituitary inhibits somatotropin release.
(18 Nov 1997)
deliberate release Generally refers to putting a genetically manipulated organism into field trials.
(14 Nov 1997)
sustained release tablet A drug product formulation that provides the required dosage initially and then maintains or repeats it at desired intervals.
Synonym: prolonged action tablet, repeat action tablet.
(05 Mar 2000)
paroxysmal cold haemoglobinuria <haematology> A rare blood disorder caused by antibodies which destroy red blood cells upon exposure to the cold.
The antibodies are formed against a specific blood group and are triggered by the cold. The cause is unknown but the disease has been associated with syphilis and some viral infections. Serum haemoglobin and urine haemoglobin are increased during the attacks.
The disease is chronic and treatment is difficult. Some cases resolve spontaneously without treatment.
Origin: Gr. Ouron = urine
(27 Sep 1997)
rose cold Allergic rhinitis occurring in the spring and early summer.
(05 Mar 2000)
warm-cold haemolysin Haemolysin which combines with red blood cells at temperatures below 20°C and are eluted at warmer temperatures, e.g., 30 to 37°C.
See: Donath-Landsteiner cold autoantibody, haemagglutinating cold autoantibody.
(05 Mar 2000)
cold <virology> A slang term that describes a viral upper respiratory infection which results from inflammation of the mucous membranes of the nasal cavity.
(27 Sep 1997)
cold abscess An abscess without heat or other usual signs of inflammation.
Synonym: tuberculous abscess.
(05 Mar 2000)
cold agglutination The agglutination of red blood cells by their own serum (see autoagglutination), or by any other serum when the blood is cooled below body temperature, but most pronounced below 25°C; the phenomenon results from cold agglutinins; may be seen occasionally in the blood of apparently normal persons or as a pathologic finding in patients with primary atypical pneumonia, infectious mononucleosis, and other viral diseases, certain protozoan infections, or lymphoproliferative neoplasms.
See: autoagglutination.
(05 Mar 2000)
cold agglutination test <investigation> A test for blood antibodies which are present in certain peculiar types of pneumonia (atypical pneumonia, Mycoplasma)
(27 Sep 1997)
cold agglutinin An antibody which reacts more efficiently at temperatures below 37°C.
(05 Mar 2000)
cold agglutinins <haematology> Antibodies that agglutinate particles with greater activity below 32­C. They are IgM antibodies specifically reactive with blood groups I and i in humans and agglutinate red blood cells on cooling, causing Raynaud's phenomenon in vivo.
(18 Nov 1997)
cold allergy Physical symptoms produced by hypersensitivity to cold.
(05 Mar 2000)
cold antibody See: cold agglutinin.
(05 Mar 2000)
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