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PC4 proprotein convertase <enzyme> Member of the kex2-subtilisin-like proprotein convertase family; there are at least three pc4 mrnas, a, b, and c (654, 619 and 609 amino acids respectively); abundant in rat testis; do not confuse with an immediate early protein pc4
Registry number: EC 3.4.21.-
Synonym: pc4 protein
(26 Jun 1999)
PC5 proprotein convertase <enzyme> Member of the subtilisin/kexin-like proprotein convertase family; isolated from mouse (mpc5) and rat (rpc5) genbank l14932 (mouse), l14933 (rat)
Registry number: EC 3.4.21.-
Synonym: pc5 protein, mpc5, rpc5, prohormone convertase pc5
(26 Jun 1999)
PC8 prohormone convertase <enzyme> Shows amino acid identity with the mammalian convertases furin (54%), pace4 (53%), pc1 (53%), and pc2 (52%); amino acid sequence given in first source
Registry number: EC 3.4.21.-
Synonym: pc8 protein
(26 Jun 1999)
convertase Proteases of complement that convert one component into another.
See: component of complement.
(05 Mar 2000)
pro-ocytocin-neurophysin convertase <enzyme> Cleaves pro-ocytocin-neurophysin at the cooh-terminal side of arg 12 to release the bioactive peptide
Registry number: EC 3.4.99.-
Synonym: pro-ot-np convertase, pro-oxytocin-neurophysin convertase
(26 Jun 1999)
somatostatin-28 convertase <enzyme> Converts somatostatin-28 to somatostatin-14 and somatostatin-28(1-12)
Registry number: EC 3.4.99.-
Synonym: s-28 convertase
(26 Jun 1999)
N-arginine dibasic convertase <enzyme> Catalyses cleavage at the n-terminus of arginine residues in dibasic stretches of proteins; located in brain cortex; genbank l27124
Registry number: EC 3.4.24.-
Synonym: nrd convertase, n-arg dibasic convertase
(26 Jun 1999)
surfactant subtype convertase <enzyme> Converts surfactant heavy subtype to light subtype; inhibited by many serine proteinase inhibitors
Registry number: EC 3.4.21.-
Synonym: pst-convertase
(26 Jun 1999)
LPC proprotein convertase <enzyme> Member of the proprotein convertase family and directly implicated in oncogeneis; amino acid sequence given in first source
Registry number: EC 3.4.21.-
Synonym: lpc gene product, lpc protein
(26 Jun 1999)
alternative oxidase pathway Pathway of mitochondrial electron transport in higher plants, particularly in fruits and seeds, that does not involve cytochrome oxidase and thus is resistant to cyanide.
(18 Nov 1997)
alternative pathway See: complement activation.
(18 Nov 1997)
anabolic pathway <biochemistry> A reaction or series of reactions in a metabolic pathway that synthesise complex molecules from simpler ones, usually requiring the input of energy.
Compare: catabolic pathway.
(09 Oct 1997)
auditory pathway Neural paths and connections within the central nervous system, beginning at the organ of Corti's hair cells, continuing along the eighth nerve, and terminating at the auditory cortex.
(05 Mar 2000)
GABA pathway The pathway that ultimately converts 4-aminobutyrate to succinate; succinate is then converted to alpha-ketoglutarate, via the tricarboxylic acid cycle, which is then acted upon by glutamate dehydrogenase; glutamate is then decarboxylated to reform 4-aminobutyrate; an important pathway for those cells which make this neuroactive molecule.
Synonym: GABA pathway.
(05 Mar 2000)
Palade pathway <cell biology> The routing of proteins from the site of their synthesis to the final cellular or secreted position. Several different pathways are known and others suspected. Glycosylation of the proteins may provide specific address labels for the proteins.
(18 Nov 1997)
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