| discrete variable | A variable that may assume only a countable (usually finite) number of values. (05 Mar 2000) |
|---|---|
| immunoglobulin variable region | That region of the immunoglobulin (antibody) molecule that varies in its amino acid sequence and composition, confers the antigenic specificity, and is thought to comprise the binding site for the antigen. It is located at the n-terminus of the fab fragment of the immunoglobulin. It includes hypervariable and framework regions, vh family subgroups, and the complementarity-determining region. (12 Dec 1998) |
| independent variable | A characteristic being measured or observed that is hypothesised to influence another event or manifestation (the dependent variable) within a defined area of relationships under study; that is, the independent variable is not influenced by the event or manifestation, but may cause it or contribute to its variation. See: dependent variable. (05 Mar 2000) |
| intermediate variable | A variable in a causal pathway that causes variation in the dependent variable and is itself caused to vary by the independent variable. (05 Mar 2000) |
| intervening variable | An event, such as an attitude or emotion, inferred to occur within an organism between the stimulation and response in such a way as to influence or determine the response. (05 Mar 2000) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| Acquired Immunodeficiency Syndrome | <immunology, syndrome> An epidemic disease caused by an infection by human immunodeficiency virus (HIV-1, HIV-2), a retrovirus that causes immune system failure and debilitation and is often accompanied by infections such as tuberculosis. AIDS is spread through direct contact with bodily fluids. Acronym: AIDS (10 May 1997) |
| bovine immunodeficiency virus | A lentivirus causing lymphocytosis in cattle. (05 Mar 2000) |
| malignancy and immunodeficiency | <radiology> High risk of malignancy (especially lymphoma/leukaemia, GI tumours): X-linked agammaglobulinaemia (Bruton's), common variable immunodeficiency, severe combined immunodeficiency (SCID kids), ataxia-telangectasia, Wiscott-Aldrich syndrome, selective IgA deficiency (12 Dec 1998) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| phagocytic dysfunction disorders immunodeficiency | Suppression in number or function of phagocytic cells such as in chronic granulomatous disease. Synonym: phagocytic dysfunction disorders immunodeficiency. Origin: L. Phagedaena, Gr Phago, To eat. (05 Mar 2000) |
| phagocytic dysfunction immunodeficiency | Suppression in number or function of phagocytic cells such as in chronic granulomatous disease. Synonym: phagocytic dysfunction disorders immunodeficiency. Origin: L. Phagedaena, Gr Phago, To eat. (05 Mar 2000) |
| combined immunodeficiency | <immunology> Congenital immunodeficiency with thymic agenesis, lymphocyte depletion and hypogammaglobulinaemia: both cellular and humoral immune systems are affected and life expectancy is low unless marrow transplantation is successful. (18 Nov 1997) |
| combined immunodeficiency syndrome | <syndrome> A serious primary immunodeficiency affecting both T and B-cells. (05 Mar 2000) |
| congenital severe combined immunodeficiency | Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes. (18 Nov 1997) |