| CRC | cardiovascular reflex conditioning; clinical research center; colorectal carcinoma; concentrated red... |
|---|---|
| HNPCC | hereditary nonpolyposis colorectal cancer |
| MCC | mean corpuscular hemoglobin concentration; medial cell column; Medical Council of Canada; metacerebr... |
| CFPR | Canadian Familial Polyposis Registry |
| FPC | familial polyposis coli; family planning clinic; fish protein concentrate |
| recessive gene | A gene that is expressed onlywhen it is present in two copies or if theother copy is missing. (09 Oct 1997) |
|---|---|
| recessive inheritance | dominance of traits |
| recessive oncogene | <molecular biology> A single copy of this gene issufficient to suppress cell proliferation, the loss of both copies of the gene contributes to cancer formation. (09 Oct 1997) |
| recessive trait | See: dominance of traits. (05 Mar 2000) |
| recessive, x-linked | A gene on the X chromosome that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, duchenne muscular dystrophy (dmd) is an x-linked recessive disorder. A dmd boy has the dmd gene on his sole x chromosome (and so is said to be hemizgous for dmd). Although it is much rarer, a girl can have dmd (by several different means as, for example, if she has the dmd gene on both her x chromosomes and so is homozygous for dmd). (12 Dec 1998) |
| multiple intestinal polyposis | Begins usually in late childhood; polyps increase in numbers, causing symptoms of chronic colitis, and carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance. In the Gardner syndrome there are extracolonic changes (desmoid tumours, etc.). Synonym: polyposis coli. Hamartomatous polyposis of the small or large intestine, Peutz-Jeghers syndrome with melanin spots on the lips, less common, miscellaneous, rare, and doubtful occurrences. Synonym: familial intestinal polyposis. (05 Mar 2000) |
| polyposis | Presence of several polyps. Origin: polyp + G. -osis, condition (05 Mar 2000) |
| polyposis coli | Hereditary disorder (Mendelian dominant) characterised by the development of hundreds of adenomatous polyps in the large intestine, which show a tendency to progress to malignancy. The APC gene has also been implicated in a chromosome 5 gastric and pancreatic cancer. (18 Nov 1997) |
| polyposis syndromes | <radiology> Inher. Malig. Type familial polyposis coli dom and adenoma Gardner syndrome dom and Turcot syndrome rec CNS Peutz-Jeghers syndrome dom (+) hamartoma Cowden syndrome dom ? juvenile polyposis coli (?) - juvenile Cronkhite-Canada syndrome (12 Dec 1998) |
| juvenile polyposis coli | <radiology> Benign polyposis, inheritance uncertain, inflammatory or retention polyps: round, smooth, soft, mucin-filled, non-neoplastic, onset less than 10 yrs, polyps can prolapse through anus, associated with diarrhoea, protein loss see: polyposis syndromes, Cronkhite-Canada syndrome (12 Dec 1998) |
| familial intestinal polyposis | Begins usually in late childhood; polyps increase in numbers, causing symptoms of chronic colitis, and carcinoma of the colon almost invariably develops in untreated cases; autosomal dominant inheritance. In the Gardner syndrome there are extracolonic changes (desmoid tumours, etc.). Synonym: polyposis coli. Hamartomatous polyposis of the small or large intestine, Peutz-Jeghers syndrome with melanin spots on the lips, less common, miscellaneous, rare, and doubtful occurrences. Synonym: familial intestinal polyposis. (05 Mar 2000) |
| familial polyposis | An inherited condition in which several hundred polyps develop in the colon and rectum. (12 Dec 1998) |
| familial polyposis coli | <gastroenterology, oncology> A inherited, disorder where there are multiple adenomatous polyps (up to several thousand) in the colon. Malignant degeneration of the polyps (to colon carcinoma) occurs in virtually 100% by age 40. Inheritance: autosomal dominant. (27 Sep 1997) |
| kidney, polycystic, autosomal recessive | Rare genetic disorder with autosomal recessive inheritance characterised by multiple cysts in both kidneys and associated hepatic lesions. Serious manifestations are usually present at birth and there is high perinatal mortality. (12 Dec 1998) |
| filiform polyposis | <radiology> Benign, non-specific sequela of diffuse, severe mucosal inflammation, UC, Crohn's, XR: thin, straight filling defects, resembles stalks of polyps without heads (12 Dec 1998) |