| sore shins | A condition seen most frequently in young thoroughbred horses during early training, and characterised by periostitis of the dorsal surface of the third metacarpal or metatarsal bone. Synonym: bucked shins. (05 Mar 2000) |
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| sore throat | A condition characterised by pain or discomfort on swallowing; it may be due to any of a variety of inflammations of the tonsils, pharynx, or larynx. (05 Mar 2000) |
| Natal's sore | Lesion of cutaneous leishmaniasis. (05 Mar 2000) |
| Delhi sore | <disease> Skin disease caused by the flagellate protozoan, Leishmania tropica. (18 Nov 1997) |
| denture sore mouth | Mucosal erythema underlying a denture base, usually representing inflammation caused by ill-fitting dentures, poor oral hygiene, or Candida albicans. (05 Mar 2000) |
| desert sore | Any of a variety of chronic non-specific cutaneous ulcers, most commonly on the shins, knees, hands, and forearms, and probably a variant of ecthyma, that occur in tropical and desert areas. Synonym: Barcoo rot, veldt sore. (05 Mar 2000) |
| Oriental sore | <disease> Skin disease caused by the flagellate protozoan, Leishmania tropica. (18 Nov 1997) |
| tropical sore | Infection with promastigotes (leptomonads) of Leishmania tropica and of leishmaniasis major inoculated into the skin by the bite of an infected sandfly, Phlebotomus (commonly P. Papatasi); it is endemic in parts of Asia Minor, northern Africa, and India, and is known by innumerable names, each indicating its locality (e.g., Aleppo, Baghdad, Delhi, or Jericho boil; Aden ulcer; Biskra button); the ulcer begins as a papule that enlarges to a nodule and then breaks down into an ulcer. Two distinctive clinical and epidemiological diseases are recognised, the more common and widespread zoonotic rural disease with a moist acute form, caused by L. Major, with reservoir rodent hosts; and an urban, anthroponotic, dry, chronic form of leishmaniasis caused by leishmaniasis tropica, without a reservoir host, and now largely controlled. See: zoonotic cutaneous leishmaniasis, anthroponotic cutaneous leishmaniasis. Synonym: juccuya, Old World leishmaniasis, tropical sore. (05 Mar 2000) |
| Lahore sore | <disease> Skin disease caused by the flagellate protozoan, Leishmania tropica. (18 Nov 1997) |
| fungating sore | A granulating chancroid. (05 Mar 2000) |
| biological products | Complex pharmaceutical substances, preparations, or agents of organic origin, usually obtained by biological methods or assay, that depend for their action on the processes affecting immunity. They are used especially in diagnosis and treatment of disease (as vaccines or pollen extracts). Biological products are differentiated from biological factors in that the latter are compounds with biological or physiological activity made by living organisms. (12 Dec 1998) |
| blood products | Biopharmaceutical products purified from human blood, such as the blood clotting factor VIII used to treat haemophiliacs. (Recombinant factor VIII is also on the market.) The term also refers to biopharmaceuticals that act on blood or the cells that make blood. These products are often produced by the cells themselves, but in such tiny amounts that extracting them from blood is impractical, and so they are genetically engineered. (14 Nov 1997) |
| gene products, env | Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesised as protein precursors (polyproteins) and later cleaved into the final products by a viral protease. (12 Dec 1998) |
| gene products, gag | Proteins coded by the retroviral gag gene. The products are usually synthesised as protein precursors or polyproteins, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. Gag is short for group-specific antigen. (12 Dec 1998) |
| gene products, nef | Products of the HIV nef gene (formerly 3'-orf gene). The products trans-suppress viral replication and function as negative regulators of transcription. Nef stands for negative factor. (12 Dec 1998) |