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transferases <enzyme> Transferases are enzymes transferring a group, for example, the methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The classification is based on the scheme "donor:acceptor group transferase".
Registry number: EC 2.
(12 Dec 1998)
transferases (other substituted phosphate groups) <enzyme> A class of enzymes that transfers substituted phosphate groups.
Registry number: EC 2.7.8
(12 Dec 1998)
acetate-CoA ligase <enzyme> An enzyme that catalyses the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates.
Chemical name: Acetate:CoA ligase (AMP-forming)
Registry number: EC 6.2.1.1
(12 Dec 1998)
acetate-succinate CoA-transferase <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA
Registry number: EC 2.8.3.-
Synonym: acetate-succinate coenzyme a-transferase
(26 Jun 1999)
acetoacetyl-CoA Intermediate in the oxidation of fatty acids and in the formation of ketone bodies; also formed from two molecules of acetyl-CoA; major role is condensation with acetyl-CoA to form the important beta-hydroxy-beta-methylglutaryl-CoA.
Synonym: acetoacetyl-coenzyme A.
(05 Mar 2000)
acetoacetyl-CoA reductase An oxidoreductase catalyzing interconversion of a 3-oxoacyl-CoA and NADPH, and the corresponding d-3-hydroxyacyl-CoA, and NADP+. A step in fatty acid synthesis.
(05 Mar 2000)
acetoacetyl-CoA synthetase <enzyme> Catalyses the conversion of acetoacetate and CoA in the presence of ATP to yield AMP, pyrophosphate and acetoacetyl-CoA; the latter is the first intermediate in cholesterogenesis; also acts more slowly on l-3-hydroxybutanoate
Registry number: EC 6.2.1.16
Synonym: acetoacetyl-CoA ligase, acetoacetate-CoA ligase, acetoacetyl-coenzyme a synthetase
(26 Jun 1999)
acetoacetyl-CoA thiolase An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase.
(05 Mar 2000)
acetyl-CoA <enzyme> Condensation product of coenzyme A and acetic acid, symbolised as CoAS~COCH3; intermediate in transfer of two-carbon fragment, notably in its entrance into the tricarboxylic acid cycle and in fatty acid synthesis.
This coenzyme plays a huge role in intermediary metabolism, in which cells synthesise, break down or use nutrient molecules for energy production, growth, etc.
Acetyl-coenzyme A synthase is found in bacteria and plants and catalyses the reaction in which acetate enters metabolic pathways and forms acetyl-coenzyme A.
Synonym: acetyl-coenzyme A, active acetate.
(05 Mar 2000)
acetyl-CoA-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase <enzyme> Transfers acetate from acetyl CoA to the sn-2-position of 1-alkyl-2-lyso-glycerophosphocholine, forming the substrate for 1-alkylglycerophosphocholine acetyltransferase (EC 2.3.1.67)
Registry number: EC 2.3.1.-
Synonym: acopc acetyltransferase, 1-alkyl-2-lyso-sn-glycero-3-phosphocholine-acetyl CoA acetyltransferase, alkyllyso-gp-acetyl-CoA acetyltransferase, acetyl-coenzyme a-1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase
(26 Jun 1999)
acetyl-CoA acetyltransferase An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis.
Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase.
(05 Mar 2000)
acetyl-CoA acylase <enzyme> An enzyme that catalyses reversibly the hydrolysis of acetyl-CoA to yield CoA and acetate. The enzyme is involved in the oxidation of fatty acids.
Chemical name: Acetyl-CoA hydrolase
Registry number: EC 3.1.2.1
(12 Dec 1998)
acetyl-CoA acyltransferase <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation.
See: acetyl-CoA acetyltransferase.
Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase.
(05 Mar 2000)
acetyl-CoA:alpha-glucosaminide acetyltransferase <enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C.
(05 Mar 2000)
acetyl CoA-(beta-aminoethyl)-L-cysteine omega-N-acetyltransferase <enzyme> Forms s-(beta-n-acetyl-aminoethyl)-l-cysteine
Registry number: EC 2.3.1.-
Synonym: acoac-acetyltransferase, acetyl coenzyme a-(beta-aminoethyl)-l-cysteine omega-n-acetyltransferase
(26 Jun 1999)
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