| coagulation factor XI | <haematology> A plasma serine protease with an apple domain. (18 Nov 1997) |
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| coagulation necrosis | A type of necrosis in which the affected cells or tissue are converted into a dry, dull, fairly homogeneous eosinophilic mass without nuclear staining, as a result of the coagulation of protein as occurs in an infarct; microscopically, the necrotic process involves chiefly the cells, and remnants of histologic elements (e.g., elastin, collagen, muscle fibres) may be recognizable, as well as "ghosts" of cells and portions of cell membranes; may be caused by heat, ischemia, and other agents that destroy tissue, including enzymes that would continue to alter the devitalised cellular substance. (05 Mar 2000) |
| coagulation profile | A test which measures the speed of blood coagulation at different steps of the coagulation pathway. (27 Sep 1997) |
| coagulation time | The time required for blood to coagulate; prolonged in haemophilia and in the presence of obstructive jaundice, some anaemias and leukaemias, and some of the infectious diseases. Synonym: clotting time. (05 Mar 2000) |
| coagulation vitamin | An obsolete term for vitamin K. (05 Mar 2000) |
| coagulative | Causing coagulation. Synonym: coagulant. (05 Mar 2000) |
| coagulopathy | <haematology> A defect in the blood clotting mechanism. Examples include haemophilia, drug-induced clotting disorder, thrombocytopenia and Von Willebrand's disease. Origin: Gr. Pathos = disease (27 Sep 1997) |
| coagulum | A clot or a curd; a soft, nonrigid, insoluble mass formed when a sol undergoes coagulation. Origin: L. A means of coagulating, rennet (05 Mar 2000) |
| coal | A natural fuel formed by partial decomposition of vegetable matter under certain environmental conditions. (12 Dec 1998) |
| coal dust | <chest medicine> Fine particulate coal dust that is a known respiratory irritant. Coal dust is the underlying cause of the occupational lung disease known as black lung. (27 Sep 1997) |
| coal oil | Rock oil, mineral oil, or natural oil, a dark brown or greenish inflammable liquid, which, at certain points, exists in the upper strata of the earth, from whence it is pumped, or forced by pressure of the gas attending it. It consists of a complex mixture of various hydrocarbons, largely of the methane series, but may vary much in appearance, composition, and properties. It is refined by distillation, and the products include kerosene, benzine, gasoline, paraffin, etc. Petroleum spirit, a volatile liquid obtained in the distillation of crude petroleum at a temperature of 170 deg Fahr, or below. The term is rather loosely applied to a considerable range of products, including benzine and ligroin. The terms petroleum ether, and naphtha, are sometimes applied to the still more volatile products, including rhigolene, gasoline, cymogene, etc. Origin: NL, fr. L. Petra a rock + oleum oil: cf. F. Petrole. Cf. Petrify, and Oil. Source: Websters Dictionary (01 Mar 1998) |
| coal tar | <pharmacology> A byproduct obtained during the breakdown of bituminous coal used in the treatment of some skin diseases (for example psoriasis). (27 Sep 1997) |
| coal tar naphtha | <chemistry> A volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation. The name is sometimes applied also to the impure commercial product or benzole, and also, but rarely, to a similar mixed product of petroleum. The Benzene nucleus or Benzene ring, is a closed chain or ring, consisting of six carbon atoms, each with one hydrogen atom attached, regarded as the type from which the aromatic compounds are derived. Structure: C6H6 Origin: From Benzoin. (06 Aug 1998) |
| coal worker's pneumoconiosis | <chest medicine> A form of chronic clung disease which develops after prolonged exposure to coal dust. Advanced disease and scarring is evident on chest X-ray. Symptoms include wheezing, chronic cough and shortness of breath. (27 Sep 1997) |
| coalescence | Fusion of originally separate parts. Synonym: concrescence. (05 Mar 2000) |
| acetyl-CoA acyltransferase | <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. See: acetyl-CoA acetyltransferase. Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase. (05 Mar 2000) |
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| acetyl-CoA:alpha-glucosaminide acetyltransferase | <enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C. (05 Mar 2000) |
| acetyl CoA-(beta-aminoethyl)-L-cysteine omega-N-acetyltransferase | <enzyme> Forms s-(beta-n-acetyl-aminoethyl)-l-cysteine Registry number: EC 2.3.1.- Synonym: acoac-acetyltransferase, acetyl coenzyme a-(beta-aminoethyl)-l-cysteine omega-n-acetyltransferase (26 Jun 1999) |
| acetyl-CoA c-acetyltransferase | <enzyme> An enzyme that catalyses the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Chemical name: Acetyl-CoA:acetyl-CoA C-acetyltransferase Registry number: EC 2.3.1.9 (12 Dec 1998) |
| acetyl-CoA c-acyltransferase | <enzyme> Enzyme that catalyses the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Chemical name: Acyl-CoA:acetyl-CoA C-acyltransferase Registry number: EC 2.3.1.16 (12 Dec 1998) |
| acetyl-CoA carboxylase | <enzyme> A carboxylating enzyme that catalyses the conversion of ATP, acetyl-CoA, and hco3- to ADP, orthophosphate, and malonyl-CoA. It is a biotinyl-protein that also catalyses transcarboxylation. The plant enzyme also carboxylates propanoyl-CoA and butanoyl-CoA Chemical name: Acetyl-CoA:carbon-dioxide ligase (ADP-forming) Registry number: EC 6.4.1.2 (12 Dec 1998) |
| acetyl CoA carboxylase phosphatase | <enzyme> Phosphatase occurs in complex with the carboxylase Registry number: EC 3.1.3.- Synonym: acc-phosphatase, acetyl coenzyme a carboxylase phosphatase (26 Jun 1999) |
| acetyl CoA-deacetylcephalosporin C acetyltransferase | <enzyme> Product of cefg gene of cephalosporium acremonium; amino acid sequence has been determined Registry number: EC 2.3.1.- Synonym: acetyl coenzyme a-decatylcephalosporin c acetyltransferase, acetyl CoA-deacetylcephalosporin c o-acetyltransferase, dcpc-atf, deacetylcephalosporin c acetyltransferase, cefg gene product (26 Jun 1999) |
| acetyl-CoA deacylase | <enzyme> An enzyme that catalyses reversibly the hydrolysis of acetyl-CoA to yield CoA and acetate. The enzyme is involved in the oxidation of fatty acids. Chemical name: Acetyl-CoA hydrolase Registry number: EC 3.1.2.1 (12 Dec 1998) |
| acetyl-CoA hydrolase | <enzyme> An enzyme that catalyses reversibly the hydrolysis of acetyl-CoA to yield CoA and acetate. The enzyme is involved in the oxidation of fatty acids. Chemical name: Acetyl-CoA hydrolase Registry number: EC 3.1.2.1 (12 Dec 1998) |
| acetyl-CoA ligase | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acetyl-CoA - lysine N6-acetyltransferase | <enzyme> First step in catabolism of lysine by saccharomyces cerevisiae Registry number: EC 2.3.1.- Synonym: accoa lysine acetyltransferase, lysine n-6-acetyltransferase, lyc1 gene product (26 Jun 1999) |
| acetyl-CoA synthetase | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acetyl-CoA thiolase | An acetyltransferase forming acetoacetyl-CoA from two molecules of acetyl-CoA, releasing one CoA. A key step in ketogenesis and sterol synthesis. Synonym: acetoacetyl-CoA thiolase, acetyl-CoA thiolase, thiolase. (05 Mar 2000) |
| acryloyl-CoA reductase | <enzyme> Clostridium kluyveri enzyme; contains fmn, ferredoxin, and flavodoxin; can act as electron donors Registry number: EC 1.3.99.- Synonym: acryloyo-coenzyme a reductase (26 Jun 1999) |