| agar-gel reaction | <immunology> The reaction between an antibody and an antigen during an immunology lab procedure where the two are allowed to diffuse toward each other through an agar-gel medium. Lines of precipitation form in the places on the gel where the two react with each other and shows where the reaction has occurred. (09 Oct 1997) |
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| agarose gel electrophoresis | <procedure> A type of electrophoresis that uses a matrix of highly purified agar to separate large nucleotides in size. (06 May 1997) |
| aluminum hydroxide gel | A suspension containing Al2O3, mainly in the form of aluminum hydroxide, used as an antacid; a dried form, with the same use, is obtained by drying the product of interaction in aqueous solution of an aluminum salt with ammonium or sodium carbonate. (05 Mar 2000) |
| aluminum phosphate gel | An aqueous suspension of between 4.0 and 5.0% of aluminum phosphate; used as an antacid. (05 Mar 2000) |
| bag-gel implant | An implant composed of a silicone rubber bag containing a silicone gel; used in augmentation mammaplasty. (05 Mar 2000) |
| gel | Jelly like material formed by the coagulation of a colloidal liquid. Many gels have a fibrous matrix and fluid filled interstices: gels are viscoelastic rather than simply viscous and can resist some mechanical stress without deformation. Examples are the gels formed by large molecules such as collagen (and gelatin), agarose, acrylamide and starch. (18 Nov 1997) |
| gel diffusion | Diffusion in a gel, as in the case of gel diffusion precipitin tests in which the immune reactants diffuse in agar. See: immunodiffusion. (05 Mar 2000) |
| gel diffusion precipitin tests | Precipitin test's in which the immune precipitate forms in a gel medium (usually agar) into which one or both reactants have diffused; generally classified in two types, in one dimension, and in two dimensions. Synonym: gel diffusion reactions. (05 Mar 2000) |
| gel diffusion precipitin tests in one dimension | Precipitin test's in which antigen solution and antibody incorporated in agar are layered in tubes, permitting effective diffusion in the vertical dimension; the antibody-containing agar may be overlaid directly with antigen solution (single (gel) diffusion in one dimension). (05 Mar 2000) |
| gel diffusion precipitin tests in two dimensions | Precipitin test's made in a layer of agar that permits radial diffusion, in both of the horizontal dimensions, of one or both reactants. Double (gel) diffusion in two dimensions (Ouchterlony test, technique, or method) incorporates antigen and antibody solutions placed in separate wells in a sheet of plain agar, permitting radial diffusion of both reactants; this method is widely used to determine antigenic relationships; the bands of precipitate that form where the reactants meet in optimal concentration are of three patterns, referred to as reaction of identity, reaction of partial identity (cross-reaction), and reaction of nonidentity. (05 Mar 2000) |
| gel diffusion reactions | Precipitin test's in which the immune precipitate forms in a gel medium (usually agar) into which one or both reactants have diffused; generally classified in two types, in one dimension, and in two dimensions. Synonym: gel diffusion reactions. (05 Mar 2000) |
| gel electrophoresis | <molecular biology> Electrophoresis using a gel supporting phase. Usually applied to systems where the gel is based on polyacrylamide. See: electrophoresis. (05 May 1997) |
| gel exclusion chromatography | <investigation> A lab technique, a type of column chromatography, used to separate the components of a mixture by molecular size and to collect the molecules which are larger than a certain size. It is similar to gel filtration, small molecules are slowed or trapped by the pores in the gel beads filling the column, while large molecules, too large to fit into the pores, slide past the beads and get to the bottom of the column first. at this point, the large molecules are collected. Gel exclusion refers to the maximum size of molecule which will fit into the gel bead pores, and this lab technique is used to collect the molecules in the mixture which are larger than, or excluded from, the pores. (09 Oct 1997) |
| gel filtration | <molecular biology> An important method for separating molecules according to molecular size by percolating the solution through beads of solvent permeated polymer that has pores of similar size to the solvent molecules. Unlike a continous filter that retards flow according to molecular size, separation is achieved because molecules that can enter the beads take a longer path (i.e. Are retarded) than those that cannot. Typical gels for protein separation are made from polyacrylamide or from flexible (Sephadex) or rigid (agarose, Sepharose) sugar polymers. The size separation range is determined by the degree of cross linking of the gel. (05 May 1997) |
| gel filtration chromatography | See: gel filtration. (05 Mar 2000) |