| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| 167Ga | radioactive Gallium(used in whole-body & brain scans) |
|---|---|
| GTN | - Stages of GTN(FIGO, WHO) 1. Stage O; Molar Pregnancy(H-Mole... |
| MBD | Minimal Brain Dysfuction |
| OBS(?) | Organic Brain Syndrome |
| 99mTc | radioactive Technetium(used in Brain Skull, Thyroid, Liver, Spleen, Bone & Lung scans) |
| brain contusion | A head injury of sufficient force to bruise the brain. The bruising of the brain will often involve the surface of the brain and cause an extravasation of blood without rupture of the pia-arachnoid. Often associated with a concussion. (27 Sep 1997) |
|---|---|
| brain death | Total cessation of brain function for 24 hours as manifested by absence of spontaneous movement, absence of spontaneous respiration, and absence of all brainstem reflexes. (12 Dec 1998) |
| brain-derived growth factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain-derived neurotrophic factor | <growth factor> Small basic protein purified from pig brain, a member of the family of neurotrophic factors that also includes Nerve Growth Factor and neurotrophin 3. In contrast to nerve growth factor, brain-derived neurotrophic factor is predominanantly (though not exclusively) localised in the CNS. It supports the survival of primary sensory neurons originating from the neural crest and ectodermal placodes that are not responsive to NGF. In the brain brain-derived neurotrophic factor has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. Acronym: BDGF (12 Dec 1998) |
| brain diseases, metabolic | Metabolic disorders which lead to pathological changes and/or functional deviations of the brain. (12 Dec 1998) |
| brain-heart infusion agar | A medium used for the isolation of fastidious microorganisms, especially fungi. (05 Mar 2000) |
| brain herniation | A condition that occurs when the brain is under abnormally increased pressure. The increased intracranial pressure forces the brain downward inside the skull. This results in typical neurologic manifestations (coma, paralysis and a unilateral dilated pupil). May occur secondary to head injury, primary or metastatic brain tumour, bacterial meningitis and brain abscess. Brain herniations may involve different portions of the brain such as the cerebellum (cerebellar herniation), uncus (uncal herniation) and transtentorial herniation of the cerebrum. (27 Sep 1997) |
| brain injury | Acute injuries to the brain, general or unspecified. (12 Dec 1998) |
| brain iron | <radiology> Normal, Infant: NONE, Adult: globus pallidum, substantia nigra, red nucleus, dentate nucleus, Aging: (adult) and putamen, Degenerative disease, Parkinson disease: putamen, SN compacta, Huntington disease: caudate, putamen, Alzheimer disease: cerebral cortex, Hallervorden-Spatz disease, MS: thalamus, putamen, Others, AVM: malformation and rim, Bleed: rim macrophages, Haemorrhagic CVA: gyral / basal ganglia MRI: low T1 and T2 signal (12 Dec 1998) |
| brain laceration | Gross tearing of neural tissue. (05 Mar 2000) |
| brain lipid | Impure cephalin possessing marked haemostatic action when locally applied. (05 Mar 2000) |
| brain mantle | Origin: L. See Pall the garment. 1. A large, square, woolen cloak which enveloped the whole person, worn by the Greeks and by certain Romans. It is the Roman name of a Greek garment. 2. A band of white wool, worn on the shoulders, with four purple crosses worked on it; a pall. The wool is obtained from two lambs brought to the basilica of St. Agnes, Rome, and blessed. It is worn by the pope, and sent to patriarchs, primates, and archbishops, as a sign that they share in the plenitude of the episcopal office. Befoer it is sent, the pallium is laid on the tomb of St. Peter, where it remains all night. 3. <zoology> The mantle of a bivalve. See Mantle. The mantle of a bird. Source: Websters Dictionary (01 Mar 1998) |
| brain metastases | <oncology, radiology> 10% of intracranial mass lesions are metastasis, 10-38% of patients with systemic cancer have brain metastasis: adults: lung, breast, GU tract, colon/rectum, melanoma, sinuses. children: neuroblastoma, embryonal rhabdomyosarcoma, Wilms tumour. Location: most in middle cerebral artery distribution at the cortex, 20% in posterior fossa. See also: haemorrhagic metastasis. (08 Mar 2000) |
| brain murmur | <neurology> Sounds produced by intracranial aneurysms or arterial venous aneurysms in congenital dysplastic angiomatosis. (05 Mar 2000) |
| brain natriuretic peptide | <hormone, protein> Brain peptide that induces diuresis, related to atrial natriuretic peptide. (18 Nov 1997) |