| CNS-L | central nervous system leukemia |
|---|---|
| ACA | abnormal coronary artery; acrodermatitis chronica atrophicans; acute cerebellar ataxia; adenocarcino... |
| ADR | activation, depression, repetition [in bone remodeling]; adrenodoxin reductase; Adriamycin; adverse ... |
| AEM | Academic Emergency Medicine [journal]; analytical electron microscopy; ambulatory electrocardiograph... |
| AEMK | ataxia episodica with myokymia |
| childhood tuberculosis | Initial (primary) infection with Mycobacterium tuberculosis, characterised by pneumonic lesions in middle parts of lungs, rarely cavitary, with rapid spread to lymph nodes in hilar and paratracheal areas; more often seen in childhood, but pattern is not limited to children. (05 Mar 2000) |
|---|---|
| childhood type tuberculosis | First infection by Mycobacterium tuberculosis, typically seen in children but also occurs in adults, characterised in the lungs by the formation of a primary complex consisting of small peripheral pulmonary focus with spread to hilar or paratracheal lymph nodes; may cavitate or heal with scarring or may progress. Synonym: childhood type tuberculosis. (05 Mar 2000) |
| chronic bullous dermatosis of childhood | A rare self-limiting bullous disease, chiefly of the trunk, perioral, and pelvic areas, with onset in the first decade, successively less severe recurrences, and total remission at adolescence; linear epidermal basement membrane zone deposit of IgA is found in involved and in normal skin. Synonym: linear IgA bullous disease in children. (05 Mar 2000) |
| chronic granulomatous disease of childhood | <radiology> Disorder of phagocytosis, two forms: X-linked recessive, autosomal recessive, usually fatal in childhood, infection by nonpathogenic organisms (catalase positive), pneumonia, osteomyelitis, diarrhoea, abdominal pain Findings: recurrent pneumonia (resolves incompletely, with abscess formation), adenopathy (big hila), hepatosplenomegaly, calcified granulomata in liver, spleen, lymph nodes, gastric antral narrowing (!) Cf: Chediak-Higashi syndrome More info: chronic granulomatous disease (12 Dec 1998) |
| schizophrenia, childhood | An obsolete concept, historically used for childhood mental disorders thought to be a form of schizophrenia. (12 Dec 1998) |
| torsion disease of childhood | A genetic, environmental, or idiopathic disorder, usually beginning in childhood or adolescence, marked by muscular contractions that distort the spine, limbs, hips, and sometimes the cranial-innervated muscles. The abnormal movements are increased by excitement and, at least initially, abolished by sleep. The musculature is hypertonic when in action, hypotonic when at rest. Hereditary forms usually begin with involuntary posturing of the foot or hand (autosomal recessive form ) or of the neck or trunk (autosomal dominant form ); both forms may progress to produce contortions of the entire body. Synonym: progressive torsion spasm, torsion disease of childhood, torsion dystonia, Ziehen-Oppenheim disease. (05 Mar 2000) |
| feeding and eating disorders of childhood | Mental disorders related to feeding and eating that are usually diagnosed in infancy or early childhood. (12 Dec 1998) |
| acute ataxia | Generalised ataxia of abrupt onset, most often caused by drug intoxications, poisonings, or vestibular neuronitis. (05 Mar 2000) |
| ataxia | <neurology> Failure of muscular coordination, irregularity of muscular action. Origin: Gr. Taxis = order (16 Dec 1997) |
| ataxia cordis | <cardiology> A condition where there is disorganised electrical conduction in the atria, resulting in ineffective pumping of blood into the ventricle. Acronym: AF (02 Jan 1998) |
| ataxia of calves | A specific cerebellar ataxia in the Jersey breed, probably a recessive genetic trait. (05 Mar 2000) |
| ataxia of lambs | Myelination failure seen in ewes on a copper-deficient diet. (05 Mar 2000) |
| ataxia-telangiectasia | <neurology, oncology> An intriguing autosomal recessive disorder in which a single defective gene produces myriad and protean effects, presents with cerebellar ataxia, telangiectasias in the eyes and skin, immune deficiency and autoimmune phenomena, propensity for lymphoid and other malignancies, excessive sensitivity to ionising radiation, increased serum alpha-fetoprotein concentrations and a tendency for chromosome breakage and translocation. A syndrome characterised by choreoathetosis beginning in childhood, progressive cerebellar ataxia, telangiectasis of conjunctiva and skin, slowly progressive mental deterioration and increasing cerebellar degeneration. There is evidence that heterozygotes show an increased susceptibility to malignancy as well, with breast cancer often cited. The gene was localised by linkage studies to chromosome 11q22-23, and recently cloned, revealing it to be homologous to the PI-3 kinase family so that prenatal diagnosis by RFLP analysis is possible. Other related genes are suspected to exist. Diagnosis in affected patients is made on clinical grounds, by detection of high concentrations of alpha-fetoprotein, and by a specialised cell culture assay for radiosensitivity and atypical radioresistant DNA synthesis. These cell culture methods are also used for prenatal diagnosis. A characteristic autopsy feature of ataxia-telangiectasia is the presence of empty basket cells in the cerebellum which results from degeneration of the previously contained Purkinje cells. Inheritance: autosomal recessive. (16 Dec 1998) |
| ataxia telangiectasia syndrome | ataxia telangiectasia |
| bovine congenital ataxia | An autosomal recessive ataxia seen in several European breeds of cattle. (05 Mar 2000) |