| histamine liberators | Substances that cause the release of histamine from mast cells or basophils. (05 Mar 2000) |
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| histamine n-methyltransferase | <enzyme> An enzyme that catalyses the transfer of a methyl group from s-adenosylmethionine to histamine, forming n-methylhistamine, the major metabolite of histamine in man. Chemical name: S-Adenosyl-L-methionine:histamine N-tele-methyltransferase Registry number: EC 2.1.1.8 (12 Dec 1998) |
| histamine release | The secretion of histamine from mast cell and basophil granules by exocytosis. This can be initiated by a number of factors, all of which involve binding of IgE, cross-linked by antigen, to the mast cell or basophil's fc receptors. Once released, histamine binds to a number of different target cell receptors and exerts a wide variety of effects. (12 Dec 1998) |
| histamine shock | The shock state produced in animals by the injection of histamine; characterised by bronchiolar spasm in the guinea pig and constriction of hepatic veins in the dog. (05 Mar 2000) |
| histamine test | A test for maximal production of gastric acidity or anacidity; after preliminary administration of an antihistamine, histamine acid phosphate is injected subcutaneously in a dose of 0.04 mg/kg of body weight, followed by analysis of gastric contents. Synonym: augmented histamine test. (05 Mar 2000) |