| 5 beta-cholestane-3 alpha,7 alpha-diol 26-hydroxylase | <enzyme> Nadp-dependent Registry number: EC 1.14.13.- (26 Jun 1999) |
|---|---|
| 7 alpha-hydroxy-4-cholesten-3-one-12 alpha monooxygenase | <enzyme> Liver microsomal enzyme active in conversion of cholesterol to cholic acid; introduces a 12 alpha-hydroxyl group into the steroid nucleus of cholesterol Registry number: EC 1.14.99.- Synonym: 7-hco-monooxygenase, hco 12 alpha-hydroxylase (26 Jun 1999) |
| alpha cell | <biology> A type of cell in the pancreas (in areas called the islets of Langerhans). Alpha cells make and release a hormone called glucagon, which raises the level of glucose (sugar) in the blood. (09 Oct 1997) |
| gene rearrangement, alpha-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the alpha-chain of antigen receptors. (12 Dec 1998) |
| genes, T-cell receptor alpha | DNA sequences encoding the alpha chain of the T-cell receptor. The genomic organization of the tcr alpha genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| receptors, antigen, T-cell, alpha-beta | T-cell receptors composed of CD3-associated alpha and beta polypeptide chains and expressed primarily in CD4+ or CD8+ T-cells. Unlike immunoglobulins, the alpha-beta T-cell receptors recognise antigens only when presented in association with major histocompatibility (MHC) molecules. (12 Dec 1998) |
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| acetyl-CoA:alpha-glucosaminide acetyltransferase | <enzyme> An enzyme involved in the synthesis of certain carbohydrate moieties on proteins. A deficiency of this enzyme leads to mucopolysaccharidosis type III C. (05 Mar 2000) |
| adrenergic alpha-agonists | Drugs that selectively bind to and activate alpha adrenergic receptors. (12 Dec 1998) |
| adrenergic alpha-antagonists | Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. (12 Dec 1998) |
| alpha | First letter of the Greek alphabet, a. (05 Mar 2000) |
| alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase | <enzyme> Incorporates n-acetyglucosamine as the third branch of complex n-glycosyl-oligosaccharide of hen oviduct Registry number: EC 2.4.1.145 Synonym: glcnac-transferase iv, n-acetylglucosaminyltransferase iv, udp-glcnac-gngn(glcnac to man alpha1-3)beta 4-n-acetylglucosaminyltransferase iv (26 Jun 1999) |
| alpha-1,4-glucan lyase | <enzyme> Degrades alpha-1,4-glucan to produce 1,5-anhydrofructose; from seaweeds gracilariopsis lemaneiformis and gracilaria verrucosa; mw 111 kD; amino acid sequence has been determined Registry number: EC 4.2.2.- Synonym: alpha-1,4-glucan 4-lyase (26 Jun 1999) |
| alpha 1-4-mannosyltransferase | <enzyme> From mycobacterium smegmatis; involved in methylmannose polysaccharide elongation; GDP-mannose is donor Registry number: EC 2.4.1.- (26 Jun 1999) |
| alpha(1-6)mannosidase | <enzyme> Human lysosomal enzyme highly specific for alpha 1-6 mannose residues; inhibited by swainsonine; not the same enzyme which is deficient in alpha-mannosidosis Registry number: EC 3.2.1.- (26 Jun 1999) |