| Crohn's disease | <disease, gastroenterology> An inflammatory disease of the gastrointestinal tract that seems to have both genetic and environmental causes, not well understood. The peak incidence of onset of this disease is between 15 and 25 years of age. Crohn's also occurs in later years between the ages of 55 and 60. Common symptoms include recurrent abdominal pains, fever, nausea, vomiting, weight loss and diarrhoea which is occasionally bloody. Complications include gastrointestinal bleeding, fistulas and anal fissures. Treatment includes anti-inflammatory drugs and corticosteroids. Surgery is successful in a select few. (27 Sep 1997) |
|---|---|
| crohn's enteris | Crohn's disease (regional enteritis) involving only the small intestine. (12 Dec 1998) |
| crohn's enterocolitis | Crohn's disease involving both the small and large intestines. (12 Dec 1998) |
| crohn's ileocolitis | Crohn's disease involving the ileum (the lowest portion of the small intestine) and the colon (the large intestine). (12 Dec 1998) |
| Crohn, Burrill | <person> U.S. Gastroenterologist, 1884-1983. See: Crohn's disease. (05 Mar 2000) |
| cromakalim | <chemical> A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (martindale, the extra phramacopoeia, 30th ed, p352) Pharmacological action: antihypertensive agents, bronchodilator agents, parasympatholytics, vasodilator agents. Chemical name: 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, trans-(+-)- (12 Dec 1998) |
| cromolyn sodium | <chemical> A chromone complex that acts by inhibiting the release of chemical mediators from sensitised mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. Pharmacological action: anti-asthmatic agents. Chemical name: 4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo-, disodium salt (12 Dec 1998) |
| Cronkhite, Leonard Jr | <person> U.S. Physician, *1919. See: Cronkhite-Canada syndrome. (05 Mar 2000) |
| cronkhite-canada syndrome | <radiology> Not inherited; no pattern, inflammatory glandular dilatation of stomach, colon, small bowel (50%), juvenile-type polyps, no malignant potential, protein and electrolyte loss, ectodermal abnormalities, alopecia, hyperpigmentation, nail loss (onycholysis), prognosis: males: remits, females: die in 6-18 months due to cachexia see: polyposis syndromes (12 Dec 1998) |
| Crooke's granules | Lumpy masses of basophilic material in the basophil cells of the anterior lobe of the pituitary, associated with Cushing's disease, or following the administration of ACTH. (05 Mar 2000) |
| Crooke's hyaline change | Replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogenous hyaline material; a characteristic finding in Cushing's syndrome, but usually not present in the cells of a basophil adenoma. Synonym: Crooke's hyaline degeneration. (05 Mar 2000) |
| Crooke's hyaline degeneration | Replacement of cytoplasmic granules of basophil cells of the anterior pituitary by homogenous hyaline material; a characteristic finding in Cushing's syndrome, but usually not present in the cells of a basophil adenoma. Synonym: Crooke's hyaline degeneration. (05 Mar 2000) |
| Crooke, Arthur | <person> English pathologist, *1905. See: Crooke's granules, Crooke's hyaline change, Crooke's hyaline degeneration. (05 Mar 2000) |
| Crookes' glass | A spectacle lens combined with metallic oxides to absorb ultraviolet or infrared rays. (05 Mar 2000) |
| Crookes, Sir William | <person> British physicist and chemist, 1832-1919; winner of the Nobel Prise in chemistry in 1907. See: Crookes' glass, Crookes-Hittorf tube. (05 Mar 2000) |