| Cobb syndrome | <syndrome> Cutaneous angiomas, usually in a dermatomal distribution on the trunk, associated with vascular abnormality of the spinal cord and resulting neurologic symptoms. Synonym: cutaneomeningospinal angiomatosis. (05 Mar 2000) |
|---|---|
| cobbler's suture | A suture with a needle attached at both ends. Synonym: cobbler's suture. (05 Mar 2000) |
| cobinamide kinase | <enzyme> From pseudomonas denitrificans; phosphorylates the hydroxyl group of the 1-amino-2-propanol residue of cobinamide in the presence of ATP to form cobinamide phosphate; occurs in a bifunctional protein with cobinamide phosphate guanylyltransferase Registry number: EC 2.7.1.- (26 Jun 1999) |
| cobinamide phosphate guanylyltransferase | <enzyme> From pseudomonas dentrificans; converts combinamide phosphate to GDP-cobinamide; occurs in a bifunctional protein with cobinamide kinase Registry number: EC 2.7.7.- Synonym: cbpg transferase (26 Jun 1999) |
| cobra | A genus of poisonous snakes of the subfamily elapinae of the family elapidae. There are six recognised species, all inhabiting africa except the asiatic (indian) cobra, naja naja. Some species "spit" their venom into the eyes of their "enemies". So-called spitting cobras show a high degree of accuracy in aiming for the eyes. The ringhals, the most highly specialised of the spitting cobras, is limited to southern africa. Its spray destroys eye tissue and can cause blindness; its bite can cause death. (moore: poisonous snakes of the world, 1980, p80) (12 Dec 1998) |
| cobra neurotoxins | Toxins, contained in cobra (naja) venom that block cholinergic receptors; two specific proteins have been described, the small (short, type I) and the large (long, type II) which also exist in other elapid venoms. (12 Dec 1998) |
| cobra toxin | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| cobra venom cofactor | <enzyme> A glycine-rich, heat-labile beta-glycoprotein found in blood. It is a proactivator of complement 3 in the alternate pathway of complement activation. Factor b is converted by factor d to c3 convertase. Registry number: EC 3.4.21.47 (12 Dec 1998) |
| cobra venom factor | A component of cobra venom that renders C3 proactivator (properdin factor B) susceptible to factor D of the properdin system, leading to activation of C3 and other components of complement and lysis of unsensitised erythrocytes. (05 Mar 2000) |
| cobra venoms | Venoms from snakes of the genus naja (family elapidae). They contain many specific proteins that have cytotoxic, haemolytic, neurotoxic, and other properties. Like other elapid venoms, they are rich in enzymes. They include cobramines and cobralysins. (12 Dec 1998) |
| cobrotoxin | A polypeptide of 62 residues; action on cells is similar to that of melittin in that it promotes disruption of membranes; used as an investigational antirheumatic agent. Synonym: cobra toxin, direct lytic factor of cobra venom. (05 Mar 2000) |
| cobyric acid | The hexa-amide of cobyrinic acid; a part of the vitamin B12 structure. Synonym: cobyrinamide, cobyrinic hexa-amide, factor V1a. (05 Mar 2000) |
| cobyric acid synthase | <enzyme> From pseudomonas denitrificans; amidates four carboxylate groups of cobyrinic acid Registry number: EC 2.6.1.- Synonym: cobq gene product (26 Jun 1999) |
| cobyrinamide | The hexa-amide of cobyrinic acid; a part of the vitamin B12 structure. Synonym: cobyrinamide, cobyrinic hexa-amide, factor V1a. (05 Mar 2000) |
| cobyrinic acid | Corrin with 8 methyl groups at positions 1, 2, 5, 7, 12, 15, 17; -CH2COOH groups at positions 2, 7, 18; -CH2CH2COOH groups at positions 3, 8, 13, 17; and divalent cobalt centreed among the four nitrogens. The acid side-chains are designated, in numerical order, a, b, c, d, e, f, g. It is a part of the vitamin B12 structure. (05 Mar 2000) |